Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4869354 | 0.85 | CES2 (0.57) | KMT2AMAPTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL11044058 | 0.81 | HPGD (0.56) | KMT2AMAPTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL7913254 | 0.80 | HPGD (0.55) | KMT2AMAPTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL9559962 | 0.78 | HPGD (0.54) | KMT2AMAPTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL2379429 | 0.78 | RAB9A (0.55) | KMT2AMAPTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL920107 | 0.78 | HPGD (0.54) | KMT2AMAPTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL5139133 | 0.77 | HPGD (0.68) | KMT2AMAPTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL4272837 | 0.77 | ALDH1A1 (0.49) | KMT2AMAPTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL7913411 | 0.77 | SMN1; SMN2 (0.52) | KMT2AMAPTALDH1A1HPGDSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL27218697 | 0.77 | HPGD (0.52) | KMT2AMAPTALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4620000-A | Method for preparing 4-hydroxycinnolines in a pH controlled system | SHELL OIL COMPANY (US) | 1986-10-28 | — | — | US | disclosed |