Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRPF1 | P55201 | 15/20 | 0.57 |
| ▸ | BRD4 | O60885 | 6/20 | 0.46 |
| ▸ | BRD9 | Q9H8M2 | 5/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.46 |
| ▸ | BRD1 | O95696 | 8/20 | 0.38 |
| ▸ | BRPF3 | Q9ULD4 | 5/20 | 0.38 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.37 |
| ▸ | S100B | P04271 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19448881 | 0.77 | BRPF1 (0.59) | BRPF1BRD4BRD9CA12CA9 | |
| SCHEMBL23797332 | 0.76 | BRPF1 (0.49) | BRPF1BRD4BRD9CA12CA9 | |
| SCHEMBL10913762 | 0.74 | MAPT (0.47) | BRPF1BRD4BRD9CA12CA9 | |
| SCHEMBL11743970 | 0.74 | BRPF1 (0.76) | BRPF1BRD4BRD9CA12CA9 | |
| SCHEMBL3263915 | 0.74 | BRPF1 (0.57) | BRPF1BRD4BRD9CA12CA9 | |
| SCHEMBL17576630 | 0.73 | S100B (0.58) | BRPF1BRD4BRD9CA12CA9 | |
| SCHEMBL7085783 | 0.73 | BRPF1 (1.00) | BRPF1BRD4BRD9CA12CA9 | |
| SCHEMBL9257087 | 0.73 | BRPF1 (0.62) | BRPF1BRD4BRD9CA12CA9 | |
| SCHEMBL25387340 | 0.72 | BRPF1 (0.53) | BRPF1BRD4BRD9CA12CA9 | |
| SCHEMBL16736495 | 0.72 | ATAD2 (0.62) | BRPF1BRD4BRD1ATAD2S100B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-61194074-A | — | — | None | — | — | JP | disclosed |
| JP-S61194074-A | 7-AMINO-1-ALKYL-6-FLUOROQUINOLIN-2(1H)-ONE AND ITS PREPARATION | SUMITOMO CHEM CO LTD | 1986-08-28 | — | — | JP | disclosed |