Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.55 |
| ▸ | RAB9A | P51151 | 8/20 | 0.55 |
| ▸ | MAPT | P10636 | 7/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 7/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | ALPL | P05186 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KLF10 | Q13118 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11426296 | 0.92 | MAPT (0.55) | MEN1KMT2ARAB9AMAPTGAA | |
| SCHEMBL11438362 | 0.86 | MAPT (0.55) | MEN1KMT2ARAB9AMAPTGAA | |
| SCHEMBL11431540 | 0.85 | MEN1 (0.55) | MEN1KMT2ARAB9AMAPTGAA | |
| SCHEMBL11434200 | 0.84 | MEN1 (0.56) | MEN1KMT2ARAB9AMAPTGAA | |
| SCHEMBL11434047 | 0.84 | CD40 (0.54) | MEN1KMT2ARAB9AMAPTNPC1 | |
| SCHEMBL11432089 | 0.84 | KCNMA1 (0.43) | MEN1KMT2ARAB9AMAPTNPC1 | |
| SCHEMBL11425747 | 0.84 | MAPT (0.55) | MEN1KMT2ARAB9AMAPTGAA | |
| SCHEMBL11427500 | 0.83 | ENPP2 (0.49) | MEN1KMT2ARAB9AMAPTNPC1 | |
| SCHEMBL11426456 | 0.82 | MEN1 (0.55) | MEN1KMT2ARAB9AMAPTGAA | |
| SCHEMBL11343138 | 0.82 | HPSE (0.46) | MEN1KMT2ARAB9AMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216166-A | Nitro precursors to amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |