Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.52 |
| ▸ | TACR2 | P21452 | 2/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | SHBG | P04278 | 1/20 | 0.52 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.52 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11443937 | 0.89 | ESR1 (0.55) | ESR1ESR2KDM4EALDH1A1ADRA2A | |
| SCHEMBL9577014 | 0.82 | CYP1A2 (0.48) | ALDH1A1TAAR1L3MBTL1TDP1IGF1R | |
| SCHEMBL19217738 | 0.82 | LPL (0.48) | ESR1KDM4EALDH1A1ADRA2ASLC6A2 | |
| SCHEMBL7675448 | 0.81 | ESR1 (0.62) | ESR1ESR2KDM4EALDH1A1ADRA2A | |
| SCHEMBL12327373 | 0.80 | AOC3 (0.47) | PTGS1PTGS2TAAR1SLC5A1HPGD | |
| SCHEMBL18657166 | 0.80 | GFER (0.54) | ALDH1A1CYP3A4CA2TDP1CYP19A1 | |
| SCHEMBL2163306 | 0.79 | ALDH1A1 (0.61) | KDM4EALDH1A1SLC6A3KMT2ATDP1 | |
| SCHEMBL14534212 | 0.79 | ESR1 (0.59) | ESR1ESR2KDM4EALDH1A1ADRA2A | |
| SCHEMBL13189671 | 0.78 | ESR1 (0.52) | ESR1ESR2KDM4EALDH1A1ADRA2A | |
| Raspberryketone SCHEMBL8759829 | 0.78 | ALDH1A1 (0.61) | ESR1ESR2KDM4EALDH1A1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4228266-A | FROM CYCLOPENTADIENE, DICYCLOPENTADIENE, ALKYL-SUBSTITUTED COMPOUNDS THEREOF AND A HYDROXYSTYRENE DERIVATIVE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1980-10-14 | — | — | US | claimed |
| US-4129557-A | CYCLOPENTADIENE, DICYCLOPENTADIENE, HYDROXYSTYRENE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1978-12-12 | — | — | US | claimed |
| EP-2606725-A1 | Phenol derivatives as antimicrobial agents | Symrise AG (DE) | 2013-06-26 | — | — | EP | disclosed |
| EP-2606725-A1 | Phenol derivatives as antimicrobial agents | Symrise AG (DE) | 2013-06-26 | — | — | EP | disclosed |
| US-20130156708-A1 | PHENOL DERIVATIVES AS ANTIMICROBIAL AGENTS | SYMRISE AG (DE) | 2013-06-20 | — | — | US | disclosed |
| US-20130156708-A1 | PHENOL DERIVATIVES AS ANTIMICROBIAL AGENTS | SYMRISE AG (DE) | 2013-06-20 | — | — | US | disclosed |
| US-20130156708-A1 | PHENOL DERIVATIVES AS ANTIMICROBIAL AGENTS | SYMRISE AG (DE) | 2013-06-20 | — | — | US | disclosed |
| US-20100317570-A1 | Composition and Method for the Treatment of Diseases Affected by a Peptide Receptor | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2010-12-16 | — | — | US | disclosed |
| CN-1459382-A | Thermosensitive recording material | FUJI PHOTO FILM CO LTD (JP) | 2003-12-03 | — | — | CN | disclosed |
| US-4594460-A | Process for selective C-alkylation of phenols | RHONE-POULENC SANTE (FR) | 1986-06-10 | — | — | US | disclosed |
| US-4228266-A | FROM CYCLOPENTADIENE, DICYCLOPENTADIENE, ALKYL-SUBSTITUTED COMPOUNDS THEREOF AND A HYDROXYSTYRENE DERIVATIVE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1980-10-14 | — | — | US | disclosed |
| US-4129557-A | CYCLOPENTADIENE, DICYCLOPENTADIENE, HYDROXYSTYRENE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1978-12-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317570-A1 | Composition and Method for the Treatment of Diseases Affected by a Peptide Receptor | GPR119, INSR, GLP1R | ESR1 942/4885ESR2 459/4885KDM4E 4783/4885 |
| US-20130156708-A1 | PHENOL DERIVATIVES AS ANTIMICROBIAL AGENTS | TYR, TH, COMT | ESR1 38/4885ESR2 357/4885KDM4E 1164/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.