SCHEMBL10909784

CC(C)C[C@H](NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)C(=O)N[C@H](C(=O)NC(=O)CCN1CCCC1=O)C(C)C

nearest known ligand 0.45

Predicted protein targets (top 7)

	gene	UniProt	supporting neighbours	confidence
▸	CTSK	P43235	8/20	0.45

▸	CTSB	P07858	3/20	0.45

▸	HTRA1	Q92743	2/20	0.45

▸	REN	P00797	2/20	0.44

▸	CAPN1	P07384	2/20	0.44

▸	CTSL	P07711	5/20	0.44

▸	CTSS	P25774	1/20	0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL11009166	0.91	CASP1 (0.44)	CTSKCTSBCTSLCTSS
SCHEMBL10907816	0.89	CTSK (0.56)	CTSKCTSBCTSLCTSS
SCHEMBL10908049	0.87	CTSK (0.49)	CTSKCTSBHTRA1RENCAPN1
SCHEMBL10908060	0.86	CTSK (0.51)	CTSKCTSBHTRA1RENCAPN1
SCHEMBL10909559	0.86	CTSK (0.51)	CTSKCTSBHTRA1RENCAPN1
SCHEMBL10905777	0.83	CTSK (0.49)	CTSKCTSBHTRA1RENCAPN1
SCHEMBL10908231	0.82	CTSK (0.47)	CTSKCTSBHTRA1RENCAPN1
SCHEMBL10907948	0.82	REN (0.48)	CTSKCTSBHTRA1RENCAPN1
SCHEMBL10909782	0.82	REN (0.48)	CTSKCTSBHTRA1RENCAPN1
SCHEMBL10909457	0.81	REN (0.54)	CTSKCTSBHTRA1RENCAPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-4613676-A	PEPTIDES	CIBA-GEIGY CORPORATION (US)	1986-09-23	—	—	US	disclosed