Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 11/20 | 0.43 |
| ▸ | CTSB | P07858 | 9/20 | 0.43 |
| ▸ | CTSS | P25774 | 4/20 | 0.42 |
| ▸ | CTSK | P43235 | 3/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10909784 | 0.91 | CTSK (0.45) | CTSLCTSBCTSSCTSK | |
| SCHEMBL11011701 | 0.84 | ITGB3 (0.45) | CTSLCTSBCTSSCTSKITGB3 | |
| SCHEMBL11012749 | 0.84 | CTSL (0.48) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL11009806 | 0.83 | CTSL (0.48) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL10443977 | 0.80 | CTSL (0.57) | CTSLCTSBCTSSCTSKITGB3 | |
| SCHEMBL11013588 | 0.79 | TACR1 (0.61) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL11015826 | 0.79 | CTSL (0.44) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL11009169 | 0.78 | CTSL (0.44) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL9551368 | 0.78 | CTSL (0.54) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL9666956 | 0.78 | CTSL (0.54) | CTSLCTSBCTSSCTSKTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0143746-A2 | 5-Amino 4-hydroxy-valeryl-substituted derivatives | CIBA-GEIGY AG (CH) | 1985-06-05 | — | — | EP | disclosed |