Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 7/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | LDHA | P00338 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10913832 | 0.94 | KMT2A (0.41) | KMT2ARAB9ANPC1MEN1ALDH1A1 | |
| SCHEMBL10912083 | 0.87 | ADRB2 (0.45) | ALDH1A1LMNAAGTR1MAPK1ADRB2 | |
| SCHEMBL10912707 | 0.86 | ADRB2 (0.48) | KMT2AMEN1LMNAMAPTADRB2 | |
| SCHEMBL10912894 | 0.86 | RAB9A (0.41) | KMT2ARAB9ANPC1MEN1ALDH1A1 | |
| SCHEMBL10716763 | 0.85 | ABCB1 (0.41) | KMT2ARAB9ANPC1MEN1ALDH1A1 | |
| SCHEMBL10912183 | 0.81 | ADRB2 (0.47) | KMT2AMEN1LMNAMAPTADRB2 | |
| SCHEMBL10911853 | 0.80 | RAB9A (0.38) | KMT2ARAB9ANPC1MEN1ALDH1A1 | |
| Dimethylamine SCHEMBL10914075 | 0.80 | RAB9A (0.43) | KMT2ARAB9ANPC1MEN1ALDH1A1 | |
| SCHEMBL10914068 | 0.79 | PABPC1 (0.45) | KMT2ARAB9ANPC1MEN1ALDH1A1 | |
| Dimethylamine SCHEMBL10912082 | 0.79 | RAB9A (0.45) | KMT2ARAB9ANPC1MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0171977-A1 | Phthalimide derivatives, compositions containing them and a process for preparing them | SANKYO COMPANY LIMITED (JP) | 1986-02-19 | — | — | EP | disclosed |