Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 2/20 | 0.45 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | FASN | P49327 | 3/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.35 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10910390 | 0.81 | CTSB (0.46) | CTSBCCR5CTSLFASNPLA2G2A | |
| SCHEMBL10908300 | 0.72 | PLA2G2A (0.53) | CTSBCTSLPLA2G2APLA2G5PTPN1 | |
| SCHEMBL9752636 | 0.71 | FASN (0.61) | FASNPLA2G2APLA2G5TSHRLMNA | |
| SCHEMBL10912936 | 0.69 | CTSB (0.62) | CTSBCTSLPLA2G2APLA2G5FFAR1 | |
| SCHEMBL10908498 | 0.69 | FASN (0.39) | FASNPLA2G2APLA2G5HPGDFFAR1 | |
| SCHEMBL14491652 | 0.66 | PTGS1 (0.43) | CCR5PTGS1PTGS2CYP1A2CYP3A4 | |
| SCHEMBL12044485 | 0.65 | FASN (0.43) | FASNPLA2G2APLA2G5PTGS1PTGS2 | |
| SCHEMBL10908576 | 0.64 | CTSB (0.64) | CTSBCTSLHSP90AA1FFAR1NFKB1 | |
| SCHEMBL9752842 | 0.64 | FASN (0.75) | FASNPLA2G2APLA2G5TSHRLMNA | |
| SCHEMBL12599531 | 0.64 | HPGD (0.42) | CTSBCCR5CTSLCYP3A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0069536-B1 | PHLOROPHENONE DERIVATIVES, PROCESSES FOR PREPARING SUCH COMPOUNDS, USES AND PHARMACEUTICAL COMPOSITIONS OF PHLOROPHENONE COMPOUNDS | NORISTAN LIMITED (ZA) | 1986-12-17 | — | — | EP | disclosed |
| US-4578520-A | Phlorophenone derivatives, processes for preparing such compounds, uses and pharmaceutical compositions of phlorophenone compounds | NORISTAN LIMITED (ZA) | 1986-03-25 | — | — | US | disclosed |
| US-4503256-A | BACTERICIDES, FUNGICIDES | NORISTAN LIMITED (ZA) | 1985-03-05 | — | — | US | disclosed |
| EP-0069536-A1 | Phlorophenone derivatives, processes for preparing such compounds, uses and pharmaceutical compositions of phlorophenone compounds | NORISTAN LIMITED (ZA) | 1983-01-12 | — | — | EP | disclosed |