SCHEMBL10912607

SCHEMBL10912607

C=C(C)c1ccccc1.C=C(CC(C)(C)c1ccccc1)c1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.43
HTT P42858 2/20 0.43
TAAR1 Q96RJ0 1/20 0.42
MAOA P21397 6/20 0.39
MAOB P27338 6/20 0.39
CYP2C19 P33261 1/20 0.39
HIF1A Q16665 1/20 0.39
MEN1 O00255 1/20 0.35
LMNA P02545 1/20 0.35
MAPK1 P28482 1/20 0.35
KMT2A Q03164 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
ME2 P23368 1/20 0.35
ME1 P48163 1/20 0.35
ME3 Q16798 1/20 0.35
ALOX15 P16050 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
KDM4E B2RXH2 1/20 0.34
MAPT P10636 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14921 0.93 TAAR1 (0.48) ALDH1A1HTTTAAR1MAOAMAOB
Carbon Tetrachloride SCHEMBL28327161 0.87 TAAR1 (0.44) ALDH1A1HTTTAAR1MAOAMAOB
SCHEMBL10910413 0.80 TAAR1 (0.44) ALDH1A1HTTTAAR1MAOAMAOB
SCHEMBL296800 0.79 MAOA (0.42) ALDH1A1TAAR1MAOAMAOBCYP2C19
SCHEMBL7172775 0.79 CYP2C19 (0.44) ALDH1A1HTTTAAR1MAOAMAOB
SCHEMBL11247276 0.79 ALDH1A1 (0.39) ALDH1A1HTTTAAR1MAOAMAOB
SCHEMBL28864314 0.79 TAAR1 (0.50) ALDH1A1HTTTAAR1CYP2C19HIF1A
SCHEMBL1019327 0.77 TAAR1 (0.48) ALDH1A1HTTTAAR1CYP2C19HIF1A
SCHEMBL2399414 0.77 MAOA (0.47) ALDH1A1MAOAMAOBCYP2C19HIF1A
Hydrogen Peroxide SCHEMBL7249472 0.76 CES2 (0.48) ALDH1A1MAOAMAOBCYP2C19MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4596896-A Containing monovinyl aromatic compound with tetrahydrothiophene-1,1-dioxide in the presence of acid catalyst PHILLIPS PETROLEUM COMPANY (US) 1986-06-24 US disclosed