SCHEMBL2399414

SCHEMBL2399414

C=C(CC(C)(C)C)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MAOA P21397 6/20 0.47
MAOB P27338 6/20 0.47
POLB P06746 1/20 0.40
GAA P10253 2/20 0.38
MAPT P10636 2/20 0.38
HPGD P15428 1/20 0.38
RAB9A P51151 1/20 0.38
CYP2C19 P33261 1/20 0.38
HIF1A Q16665 1/20 0.38
EGFR P00533 1/20 0.37
ALDH1A1 P00352 1/20 0.37
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14921 0.83 TAAR1 (0.48) MAOAMAOBCYP2C19HIF1AALDH1A1
SCHEMBL8676203 0.83 MAOA (0.44) MAOAMAOBMAPTCYP2C19HIF1A
SCHEMBL296800 0.81 MAOA (0.42) MAOAMAOBMAPTCYP2C19HIF1A
SCHEMBL5033208 0.81 MAOA (0.42) MAOAMAOBMAPTHPGDCYP2C19
SCHEMBL3382150 0.79 PPARA (0.43) MAOAMAOBPOLBMAPTHPGD
SCHEMBL5072554 0.79 MAOA (0.43) MAOAMAOBPOLB
SCHEMBL23792833 0.78 CYP19A1 (0.39) MAOA
SCHEMBL5039116 0.78 MAOA (0.44) MAOAMAOBPOLBMAPTALDH1A1
SCHEMBL10486356 0.77 MAOA (0.47) MAOAMAOBPOLBMAPTHPGD
SCHEMBL7792764 0.77 ESR1 (0.47) MAOAMAOBMAPTHPGDMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108484820-A A kind of synthetic method of novel acrylic ester lotion 中国林业科学研究院林产化学工业研究所 2018-09-04 CN claimed
CN-115703723-B Acrylamide compound, heat-resistant salt-resistant polyacrylamide for oil displacement, and preparation method and application thereof 中国石油化工股份有限公司 2024-03-26 CN disclosed
CN-115703723-A Acrylamide compound, heat-resistant salt-tolerant polyacrylamide for oil displacement, and preparation method and application thereof 中国石油化工股份有限公司 2023-02-17 CN disclosed
US-20210238336-A1 FUNCTIONALIZED POLYMERS HAVING THERMORESPONSIVE BEHAVIOR BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC 2021-08-05 US disclosed
CN-108484820-A A kind of synthetic method of novel acrylic ester lotion 中国林业科学研究院林产化学工业研究所 2018-09-04 CN disclosed
US-8012628-B2 Polymer electrochemical device KURARAY CO., LTD. (JP) 2011-09-06 US disclosed
US-20080014505-A1 POLYMER ELECTROCHEMICAL DEVICE KURARAY CO., LTD. (JP) 2008-01-17 US disclosed
EP-1870597-A2 Polymer electrochemical device Kuraray Co., Ltd. (JP) 2007-12-26 EP disclosed
EP-0770888-B1 Low water-absorptive ocular lens material, low water-absorptive ocular lens shaped product made thereof, low water-absorptive ocular lens made thereof and process for its production MENICON CO LTD (JP) 2004-08-04 EP disclosed
EP-0843184-B1 Ocular lens material MENICON CO LTD (JP) 2004-03-03 EP disclosed
US-5811502-A CONTAINING COPOLYMERS OF METHACRYLIC ESTERS AND HAVING OXYGEN PERMEABILITY, SUFFICIENT HARDNESS AND WETTABILITY MENICON CO., LTD. (JP) 1998-09-22 US disclosed
EP-0854369-A2 Ocular lens material Menicon Co., Ltd. (JP) 1998-07-22 EP disclosed
US-5777032-A ACRYLATE POLYMER AND SILICONE POLYMER MENICON CO., LTD. (JP) 1998-07-07 US disclosed
EP-0843184-A2 Ocular lens material Menicon Co., Ltd. (JP) 1998-05-20 EP disclosed
US-5670594-A POLYDIMETHYLSILOXANE POLYMERS WITH VINYL OR ACRYLATE GROUPS FOR INTRAOCULAR LENSES MENICON CO., LTD. (JP) 1997-09-23 US disclosed
EP-0794440-A2 Ocular lens and a method for its production Menicon Co., Ltd. (JP) 1997-09-10 EP disclosed
EP-0770888-A2 Low water-absorptive ocular lens material, low water-absorptive ocular lens shaped product made thereof, low water-absorptive ocular lens made thereof and process for its production Menicon Co., Ltd. (JP) 1997-05-02 EP disclosed
EP-0762149-A2 Water-absorptive soft ocular lens material, water-absorptive soft ocular lens shaped product made thereof, water-absorptive soft ocular lens made thereof and process for its production Menicon Co., Ltd. (JP) 1997-03-12 EP disclosed
US-4546131-A COPOLYMERS OF ETHYLENICALLY UNSATURATED COMPOUNDS AND ALKENYLPHENYL CYANATE THE DOW CHEMICAL COMPANY (US) 1985-10-08 US disclosed
US-4426491-A UNSATURATED ANHYDRIDE, POLYOL, POLYAMINE OR AMINOALCOL, UNSATURATED COMPOUND UNION CARBIDE CORPORATION (US) 1984-01-17 US disclosed