Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | DPP4 | P27487 | 1/20 | 0.51 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10916891 | 0.83 | AMY1A (0.48) | KDM4ELMNAMEN1KMT2AAMY1A | |
| SCHEMBL10916886 | 0.83 | AMY1A (0.48) | KDM4ELMNAMEN1KMT2AAMY1A | |
| SCHEMBL10916847 | 0.82 | CA12 (0.65) | KDM4ELMNAMEN1KMT2ACA12 | |
| SCHEMBL28835623 | 0.80 | GSK3B (0.64) | KDM4ELMNAMEN1KMT2AAMY1A | |
| SCHEMBL1150142 | 0.80 | CASP3 (0.55) | KDM4EMEN1KMT2ACA12CA9 | |
| SCHEMBL1832812 | 0.79 | CA12 (0.60) | LMNASCN2ACA12CA9CA1 | |
| SCHEMBL11791806 | 0.78 | ALDH1A1 (0.55) | KDM4ELMNAMEN1KMT2ACA12 | |
| SCHEMBL28532343 | 0.77 | ALDH1A1 (0.60) | KDM4ELMNAMEN1KMT2APTPN1 | |
| SCHEMBL14598270 | 0.77 | ALDH1A1 (0.51) | KDM4EMEN1KMT2ASCN2ACA12 | |
| SCHEMBL29531485 | 0.77 | CA1 (0.62) | KDM4ESCN2ACA12CA9CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0055562-B1 | CEPHALOSPORIN DERIVATIVES | ICI PHARMA (FR) | 1986-02-12 | — | — | EP | disclosed |
| US-4492692-A | BACTERICIDE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-01-08 | — | — | US | disclosed |
| EP-0055562-A2 | Cephalosporin derivatives | ICI PHARMA (FR) | 1982-07-07 | — | — | EP | disclosed |