Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 7/20 | 0.37 |
| ▸ | CYSLTR1 | Q9Y271 | 7/20 | 0.37 |
| ▸ | BID | P55957 | 3/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.37 |
| ▸ | PPARA | Q07869 | 3/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.37 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.37 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | EP300 | Q09472 | 1/20 | 0.37 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.37 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.37 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.37 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL15158200 | 0.99 | CYSLTR2 (0.39) | CYSLTR2CYSLTR1BIDMCL1PPARA | |
| Potassium Ion SCHEMBL10975559 | 0.99 | CYSLTR2 (0.39) | CYSLTR2CYSLTR1BIDMCL1PPARA | |
| Potassium Ion SCHEMBL10553099 | 0.99 | CYSLTR2 (0.39) | CYSLTR2CYSLTR1BIDMCL1PPARA | |
| Potassium Ion SCHEMBL11006548 | 0.99 | CYSLTR2 (0.39) | CYSLTR2CYSLTR1BIDMCL1PPARA | |
| Potassium Ion SCHEMBL184557 | 0.99 | CYSLTR2 (0.39) | CYSLTR2CYSLTR1BIDMCL1PPARA | |
| Potassium Ion SCHEMBL2503961 | 0.99 | CYSLTR2 (0.39) | CYSLTR2CYSLTR1BIDMCL1PPARA | |
| Zinc Ion SCHEMBL15157722 | 0.97 | CYSLTR2 (0.39) | CYSLTR2CYSLTR1BIDMCL1PPARA | |
| SCHEMBL11005399 | 0.97 | CYSLTR2 (0.39) | CYSLTR2CYSLTR1BIDMCL1PPARA | |
| SCHEMBL11608341 | 0.97 | CYSLTR2 (0.39) | CYSLTR2CYSLTR1BIDMCL1PPARA | |
| Zinc Ion SCHEMBL15158157 | 0.97 | CYSLTR2 (0.39) | CYSLTR2CYSLTR1BIDMCL1PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4594150-A | Flotation of metal sulfides from ore | SOCIETE NATIONALE ELF AQUITAINE (PRODUCTION) (FR) | 1986-06-10 | — | — | US | disclosed |