Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 4/20 | 0.52 |
| ▸ | RARB | P10826 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | RARA | P10276 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.42 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9850104 | 0.86 | ALDH1A1 (0.54) | HSD11B1RARBMEN1ALDH1A1MAPT | |
| SCHEMBL10919516 | 0.84 | RARB (0.49) | HSD11B1RARBMEN1ALDH1A1MAPT | |
| SCHEMBL5599432 | 0.78 | HSD11B1 (0.61) | HSD11B1RARBMEN1ALDH1A1MAPT | |
| SCHEMBL35867 | 0.78 | HSD11B1 (0.61) | HSD11B1RARBMEN1ALDH1A1MAPT | |
| SCHEMBL10922359 | 0.78 | MAPT (0.58) | HSD11B1RARBMEN1ALDH1A1MAPT | |
| SCHEMBL10559262 | 0.78 | RARB (0.54) | HSD11B1RARBMEN1ALDH1A1MAPT | |
| Hydrogen Sulfide SCHEMBL27798487 | 0.77 | HSD11B1 (0.59) | HSD11B1RARBMEN1ALDH1A1MAPT | |
| Phosphine SCHEMBL27456116 | 0.77 | HSD11B1 (0.59) | HSD11B1RARBMEN1ALDH1A1MAPT | |
| Phosphine SCHEMBL27545611 | 0.77 | HSD11B1 (0.59) | HSD11B1RARBMEN1ALDH1A1MAPT | |
| Hydrogen Sulfide SCHEMBL28025844 | 0.77 | HSD11B1 (0.59) | HSD11B1RARBMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0104011-B1 | PYRIMIDINE DERIVATIVES | Chisso Corporation (JP) | 1986-04-23 | — | — | EP | disclosed |
| US-4533488-A | COMPONENT OF LIQUID CRYSTAL COMPOSITIONS | CHISSO CORPORATION (JP) | 1985-08-06 | — | — | US | disclosed |
| EP-0104011-A1 | Pyrimidine derivatives | Chisso Corporation (JP) | 1984-03-28 | — | — | EP | disclosed |