Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 6/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 7/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL303568 | 0.90 | HCAR2 (0.39) | HCAR2ATMMAPTCA12CA1 | |
| SCHEMBL109189 | 0.83 | TSHR (0.47) | HCAR2LMNAALDH1A1NPSR1HSD17B10 | |
| Propane SCHEMBL28656089 | 0.82 | TSHR (0.46) | HCAR2ALDH1A1NPSR1HSD17B10 | |
| SCHEMBL3959259 | 0.81 | HCAR2 (0.47) | HCAR2ATMMAPTCA12CA1 | |
| SCHEMBL3963683 | 0.77 | HCAR2 (0.42) | HCAR2ATMMAPTLMNAHTT | |
| SCHEMBL76913 | 0.77 | ALDH1A1 (0.52) | LMNAALDH1A1RAB9AHSD17B10 | |
| SCHEMBL16681370 | 0.76 | ATM (0.57) | HCAR2ATMMAPTALDH1A1NPSR1 | |
| SCHEMBL14777782 | 0.76 | ATM (0.57) | HCAR2ATMMAPTALDH1A1NPSR1 | |
| SCHEMBL110602 | 0.76 | ATM (0.57) | HCAR2ATMMAPTALDH1A1NPSR1 | |
| SCHEMBL29631686 | 0.76 | ALOX15 (0.54) | LMNAALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009147024-A1 | BINDERS BASED ON POLYMERS CONTAINING ALPHA-SILANE GROUPS | WACKER CHEMIE AG (DE) | 2009-12-10 | — | — | WO | disclosed |
| WO-2009033908-A2 | MOISTURE CROSS-LINKABLE POLYMERS BASED ON ALPHA-HETEROATOM SUBSTITUTED SILANES | WACKER CHEMIE AG (DE) | 2009-03-19 | — | — | WO | disclosed |