Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | AGER | Q15109 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10838063 | 0.82 | HIF1A (0.51) | POLBLMNACYP2D6HIF1AADRB2 | |
| SCHEMBL5878404 | 0.75 | L3MBTL1 (0.61) | LMNACYP2D6HIF1AL3MBTL1ADRB2 | |
| SCHEMBL4019175 | 0.75 | L3MBTL1 (0.61) | LMNACYP2D6HIF1AL3MBTL1ADRB2 | |
| SCHEMBL2021875 | 0.75 | L3MBTL1 (0.61) | LMNACYP2D6HIF1AL3MBTL1ADRB2 | |
| SCHEMBL6264190 | 0.74 | HIF1A (0.57) | POLBLMNACYP2D6HIF1AL3MBTL1 | |
| SCHEMBL267463 | 0.74 | LMNA (0.68) | POLBLMNACYP2D6HIF1AL3MBTL1 | |
| SCHEMBL258823 | 0.74 | HIF1A (0.75) | POLBLMNACYP2D6HIF1AADRB2 | |
| Hydrochloric Acid SCHEMBL6539516 | 0.73 | L3MBTL1 (0.64) | POLBLMNACYP2D6HIF1AL3MBTL1 | |
| Hydrochloric Acid SCHEMBL4925995 | 0.73 | L3MBTL1 (0.64) | POLBLMNACYP2D6HIF1AL3MBTL1 | |
| SCHEMBL31414644 | 0.73 | ALDH1A1 (0.67) | POLBLMNACYP2D6HIF1AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0194750-A1 | Dihydropyridine alkanol amines, process for their preparation and pharmaceutical compositions containing them | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-09-17 | — | — | EP | disclosed |