Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | STAT6 | P42226 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TNF | P01375 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10979942 | 0.81 | SMN1; SMN2 (0.58) | DNMT3ASMN1; SMN2LMNASTAT6KMT2A | |
| SCHEMBL3477048 | 0.79 | KMT2A (0.77) | DNMT3ASMN1; SMN2LMNASTAT6KMT2A | |
| SCHEMBL10919675 | 0.78 | ADRB2 (0.49) | DNMT3ASMN1; SMN2LMNASTAT6KMT2A | |
| SCHEMBL28377896 | 0.78 | SMN1; SMN2 (0.54) | DNMT3ASMN1; SMN2LMNASTAT6KMT2A | |
| SCHEMBL29585279 | 0.78 | SMN1; SMN2 (0.54) | DNMT3ASMN1; SMN2LMNASTAT6KMT2A | |
| SCHEMBL31561667 | 0.76 | SMN1; SMN2 (0.53) | DNMT3ASMN1; SMN2LMNASTAT6KMT2A | |
| SCHEMBL12420180 | 0.76 | SMN1; SMN2 (0.50) | DNMT3ASMN1; SMN2LMNASTAT6KMT2A | |
| SCHEMBL29833599 | 0.76 | SMN1; SMN2 (0.56) | DNMT3ASMN1; SMN2LMNASTAT6KMT2A | |
| SCHEMBL29833600 | 0.76 | SMN1; SMN2 (0.56) | DNMT3ASMN1; SMN2LMNASTAT6KMT2A | |
| SCHEMBL857765 | 0.76 | SMN1; SMN2 (0.61) | DNMT3ASMN1; SMN2LMNASTAT6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115594624-A | Preparation method of N-terminal alkenyl azaarene | 长沙资材科技有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |
| US-4587361-A | N-(4-(1-PHENYLETHENYL)PHENYL)-2-HYDROXY-3,5-DIHALOBENZAMIDE | SMITHKLINE BECKMAN CORPORATION (US) | 1986-05-06 | — | — | US | disclosed |