SCHEMBL10920184

SCHEMBL10920184

OCc1c(F)cc(F)c(-c2ccccc2)c1F

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GCGR P47871 3/20 0.37
CBFB Q13951 1/20 0.37
PRKAA2 P54646 1/20 0.35
BACE1 P56817 1/20 0.34
DHODH Q02127 1/20 0.33
NOTUM Q6P988 3/20 0.33
TSHR P16473 2/20 0.32
PRKAG1 P54619 1/20 0.32
PRKAA1 Q13131 1/20 0.32
PRKAB1 Q9Y478 1/20 0.32
MEN1 O00255 1/20 0.32
FABP2 P12104 1/20 0.32
AKR1C4 P17516 1/20 0.32
ADRA2B P18089 1/20 0.32
CHRM3 P20309 1/20 0.32
PTGS1 P23219 1/20 0.32
HTR2C P28335 1/20 0.32
PTGS2 P35354 1/20 0.32
DRD3 P35462 1/20 0.32
AKR1C3 P42330 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11050015 0.81 L3MBTL1 (0.34) PRKAG1PRKAA1PRKAB1
SCHEMBL10749204 0.81 CYP1A2 (0.33) TSHRPRKAG1PRKAA1PRKAB1
SCHEMBL3833453 0.79 BACE1 (0.40) CBFBBACE1DHODHTSHRMEN1
SCHEMBL10880447 0.77 GCGR (0.39) GCGRPRKAA2BACE1DHODHNOTUM
SCHEMBL31551665 0.76 AKR1C2 (0.47) BACE1DHODHNOTUMTSHRPTGS1
SCHEMBL10918631 0.76 LMNA (0.39) BACE1DHODHAKR1C2AKR1C1
SCHEMBL10344156 0.75 GCGR (0.40) GCGRPRKAA2BACE1NOTUMTSHR
SCHEMBL11420344 0.73 NR4A2 (0.46) BACE1DHODHTSHRMEN1FABP2
SCHEMBL12679970 0.73 GCGR (0.52) GCGRBACE1NOTUMTSHR
SCHEMBL25275054 0.72 BACE1 (0.39) BACE1DHODHTSHRMEN1FABP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012150221-A2 NOVEL HALOGENATED BENZYL ALCOHOL ESTERS OF CYCLOPROPANE CARBOXYLIC ACID AS PEST CONTROL AGENTS BAYER CROPSCIENCE AG (DE) 2012-11-08 WO disclosed
WO-2012150208-A1 USE OF SUBSTITUTED BENZYL ALCOHOL ESTERS OF CYCLOPROPANECARBOXYLIC ACID FOR CONTROLLING INSECTICIDE-RESISTANT INSECTS BAYER CROPSCIENCE AG (DE) 2012-11-08 WO disclosed
EP-0049977-B1 INSECTICIDAL (1,1'-BIPHENYL)-3-YLMETHYL ESTERS, THEIR PRODUCTION AND USE AND COMPOSITIONS CONTAINING THEM FMC Corporation (US) 1986-02-26 EP disclosed
US-4536591-A Insecticidal [1,1'-biphenyl]-3-ylmethyl esters FMC CORPORATION (US) 1985-08-20 US disclosed
EP-0125248-A1 INSECTICIDAL SUBSTITUTED-BIPHENYLMETHYL OXIME ETHERS FMC Corporation (US) 1984-11-21 EP disclosed
WO-1984001772-A1 INSECTICIDAL SUBSTITUTED-BIPHENYLMETHYL OXIME ETHERS FMC CORP (US) 1984-05-10 WO disclosed
US-4434182-A Insecticidal substituted-biphenylmethyl oxime ethers FMC CORPORATION (US) 1984-02-28 US disclosed
US-4402973-A Insecticidal (1,1'-biphenyl)-3-ylmethyl esters FMC CORPORATION (US) 1983-09-06 US disclosed
US-4329518-A INSECTICIDES, ACARICIDES, MITICIDES FMC CORPORATION (US) 1982-05-11 US disclosed
EP-0049977-A1 Insecticidal (1,1'-biphenyl)-3-ylmethyl esters, their production and use and compositions containing them FMC Corporation (US) 1982-04-21 EP disclosed