Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 3/20 | 0.40 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TYMP | P19971 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10880447 | 0.90 | GCGR (0.39) | GCGRPRKAA2TSHRLMNAMAPT | |
| SCHEMBL12679970 | 0.77 | GCGR (0.52) | GCGRTSHRLMNAMAPTHTT | |
| SCHEMBL247368 | 0.77 | LMNA (0.48) | LMNAMAPTHTTTYMPALDH1A1 | |
| SCHEMBL7713106 | 0.77 | LMNA (0.48) | LMNAMAPTHTTBACE1TYMP | |
| SCHEMBL10320031 | 0.75 | GCGR (0.50) | GCGRTSHRLMNAMAPTHTT | |
| SCHEMBL10920184 | 0.75 | GCGR (0.37) | GCGRPRKAA2TSHRMEN1KMT2A | |
| SCHEMBL7704707 | 0.74 | LMNA (0.46) | LMNAMAPTHTTTYMPALDH1A1 | |
| SCHEMBL6402127 | 0.74 | LMNA (0.46) | LMNAMAPTHTTTYMPALDH1A1 | |
| SCHEMBL7711087 | 0.74 | ALDH1A1 (0.50) | LMNAMAPTHTTTYMPNOTUM | |
| SCHEMBL10765844 | 0.73 | GCGR (0.35) | GCGRTSHRHTTPDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0221635-B1 | FLUORO ALCOHOLS AND INSECTICIDAL ESTERS THEREOF | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-03-14 | — | — | EP | disclosed |
| US-4714790-A | Fluoro alcohols and insecticidal esters thereof | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-12-22 | — | — | US | disclosed |
| EP-0221635-A1 | Fluoro alcohols and insecticidal esters thereof | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-05-13 | — | — | EP | disclosed |