SCHEMBL1092083

SCHEMBL1092083

C=CCOc1ccc(C(C)=O)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.61
GAA P10253 1/20 0.59
MAPT P10636 5/20 0.57
RAB9A P51151 4/20 0.57
NPC1 O15118 4/20 0.57
POLB P06746 2/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
LMNA P02545 1/20 0.56
NPSR1 Q6W5P4 1/20 0.56
HPGD P15428 1/20 0.53
MAOB P27338 6/20 0.53
ALDH1A1 P00352 1/20 0.51
CHRNB2 P17787 2/20 0.51
CHRNB4 P30926 2/20 0.51
CHRNA3 P32297 2/20 0.51
CHRNA4 P43681 2/20 0.51
MAOA P21397 2/20 0.50
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10541266 0.95 L3MBTL1 (0.56) L3MBTL1GAAMAPTRAB9ANPC1
SCHEMBL18766371 0.85 NPC1 (0.56) L3MBTL1MAPTRAB9ANPC1POLB
SCHEMBL826744 0.85 NPC1 (0.56) L3MBTL1GAAMAPTRAB9ANPC1
SCHEMBL10262915 0.84 L3MBTL1 (0.60) L3MBTL1GAAMAPTRAB9ANPC1
SCHEMBL10261920 0.84 L3MBTL1 (0.60) L3MBTL1GAAMAPTRAB9ANPC1
SCHEMBL10267917 0.84 L3MBTL1 (0.65) L3MBTL1GAAMAPTRAB9APOLB
SCHEMBL11853573 0.83 L3MBTL1 (0.47) L3MBTL1GAAMAPTRAB9ANPC1
SCHEMBL11853579 0.83 L3MBTL1 (0.47) L3MBTL1GAAMAPTRAB9ANPC1
SCHEMBL24890713 0.83 NPC1 (0.55) L3MBTL1MAPTRAB9ANPC1POLB
SCHEMBL1489146 0.83 ALDH1A1 (0.67) L3MBTL1MAPTRAB9ANPC1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-1029337-A None JP disclosed
CN-120536025-A Epoxy coating based on amino-terminated polyarylether oligomer and preparation method thereof 无锡中油瑞德防腐科技有限公司 2025-08-26 CN disclosed
EP-2655308-B1 PROCESS FOR THE MANUFACTURE OF DIBENZOYLMETHANE DERIVATIVES DSM IP ASSETS BV (NL) 2018-03-07 EP disclosed
US-20170259099-A1 SILICON-CONTAINING ORGANIC ACID DERIVATIVES AS ENVIRONMENTALLY FRIENDLY AFFF EXTINGUISHING AGENTS UNIVERSITÄT ZU KÖLN (DE) 2017-09-14 US disclosed
US-9561993-B2 Process for the manufacture of dibenzoylmethane derivatives DSM IP ASSETS B.V. (NL) 2017-02-07 US disclosed
US-20140017183-A1 PROCESS FOR THE MANUFACTURE OF DIBENZOYLMETHANE DERIVATIVES DSM IP ASSETS B.V. (NL) 2014-01-16 US disclosed
EP-2655308-A1 PROCESS FOR THE MANUFACTURE OF DIBENZOYLMETHANE DERIVATIVES DSM IP Assets B.V. (NL) 2013-10-30 EP disclosed
WO-2012084770-A1 PROCESS FOR THE MANUFACTURE OF DIBENZOYLMETHANE DERIVATIVES DSM IP ASSETS B.V. (NL) 2012-06-28 WO disclosed
US-8153634-B2 Carbinol derivatives having cyclic linker KOWA COMPANY, LTD. (JP) 2012-04-10 US disclosed
EP-2281817-A1 SUBSTITUTED CARBINOL COMPOUND HAVING CYCLIC LINKER Kowa Company, Ltd. (JP) 2011-02-09 EP disclosed
US-5021512-A Curable LOCTITE (IRELAND) LTD. (IE) 1991-06-04 US disclosed
JP-S6429337-A CHALCONE DERIVATIVE COMPOUND NIPPON OILS & FATS CO LTD 1989-01-31 JP disclosed
EP-0162572-B1 SILOXANE POLYPHOTOINITIATORS OF THE SUBSTITUTED ACETOPHENONE TYPE LOCTITE CORPORATION (US) 1989-01-25 EP disclosed
US-4732956-A Styryloxy resins and compositions thereof LOCTITE (IRELAND) LTD. (IE) 1988-03-22 US disclosed
EP-0229033-A2 Thiol/ene compositions LOCTITE (IRELAND) Ltd. (IE) 1987-07-15 EP disclosed
EP-0220831-A2 Styryloxy resins and polymerization process LOCTITE (IRELAND) Ltd. (IE) 1987-05-06 EP disclosed
EP-0213893-A2 Photopolymerisable compositions containing substituted pyrylium salts as photoinitiators; and novel pyrylium salts for use therein Loctite (Ireland) Limited (IE) 1987-03-11 EP disclosed
EP-0165769-A2 Polyfunctional styryloxy compounds and method of forming a cross-linked polymer LOCTITE (IRELAND) Ltd. (IE) 1985-12-27 EP disclosed
US-4543397-A PERMANENT COLORATION IN CURED PRODUCTS LOCTITE (IRELAND) LTD. (IE) 1985-09-24 US disclosed
US-4534838-A Siloxane polyphotoinitiators of the substituted acetophenone type LOCTITE CORPORATION (US) 1985-08-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140017183-A1 PROCESS FOR THE MANUFACTURE OF DIBENZOYLMETHANE DERIVATIVES DDT, DHPS, BCDIN3D L3MBTL1 2015/4885GAA 2239/4885MAPT 1616/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.