Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9786587 | 0.67 | MAPT (0.50) | KMT2AMEN1POLBLMNASMN1; SMN2 | |
| SCHEMBL11738124 | 0.65 | MEN1 (0.62) | KMT2AMEN1POLBLMNASMN1; SMN2 | |
| SCHEMBL10099725 | 0.64 | GAA (0.83) | KMT2AMEN1POLBLMNASMN1; SMN2 | |
| SCHEMBL4737020 | 0.63 | MAOB (0.51) | KMT2AMEN1POLBLMNASMN1; SMN2 | |
| SCHEMBL28901021 | 0.63 | NPC1 (0.67) | KMT2AMEN1POLBLMNASMN1; SMN2 | |
| SCHEMBL935849 | 0.62 | ALDH1A1 (0.64) | KMT2AMEN1POLBLMNASMN1; SMN2 | |
| SCHEMBL6302055 | 0.62 | GAA (0.64) | KMT2AMEN1POLBLMNASMN1; SMN2 | |
| SCHEMBL9786648 | 0.61 | LMNA (0.42) | KMT2AMEN1POLBLMNASMN1; SMN2 | |
| SCHEMBL2615418 | 0.61 | KMT2A (0.81) | KMT2AMEN1POLBLMNASMN1; SMN2 | |
| SCHEMBL20560273 | 0.61 | GAA (0.57) | KMT2AMEN1POLBLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0078546-B1 | NOVEL IMIDAZOLECARBOXAMIDE DERIVATIVES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1986-11-12 | — | — | EP | disclosed |
| EP-0078546-A1 | Novel imidazolecarboxamide derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1983-05-11 | — | — | EP | disclosed |