Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | LIPE | Q05469 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ALPG | P10696 | 1/20 | 0.45 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21634013 | 0.85 | KMT2A (0.48) | KCNH2ALOX15NR2E1L3MBTL1SMN1; SMN2 | |
| SCHEMBL21634014 | 0.85 | KMT2A (0.48) | KCNH2ALOX15NR2E1L3MBTL1SMN1; SMN2 | |
| SCHEMBL7775128 | 0.85 | CYP1A2 (0.65) | CA1CA2CA7CA9LIPE | |
| SCHEMBL6075106 | 0.83 | RAB9A (0.59) | MAPTL3MBTL1LMNACYP1A2LTA4H | |
| SCHEMBL6797677 | 0.83 | RAB9A (0.59) | MAPTL3MBTL1LMNACYP1A2LTA4H | |
| SCHEMBL10926521 | 0.82 | KMT2A (0.53) | KCNH2ALOX15NR2E1CA1CA2 | |
| SCHEMBL773087 | 0.80 | MAOB (0.59) | MAPK1SMN1; SMN2TSHR | |
| SCHEMBL3716211 | 0.79 | CYP1A2 (0.72) | KCNH2ALOX15NR2E1MAPTL3MBTL1 | |
| SCHEMBL11711802 | 0.79 | ALOX15 (0.66) | KCNH2ALOX15NR2E1L3MBTL1LMNA | |
| SCHEMBL16633105 | 0.79 | CA1 (0.73) | CA1CA2CA7CA9MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0171702-A1 | Benzoxazinone derivatives, preparation and use | BEECHAM GROUP PLC (GB) | 1986-02-19 | — | — | EP | disclosed |