Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 4/20 | 0.53 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.53 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.50 |
| ▸ | F2 | P00734 | 4/20 | 0.49 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.49 |
| ▸ | NTSR2 | O95665 | 1/20 | 0.47 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.47 |
| ▸ | APLNR | P35414 | 1/20 | 0.47 |
| ▸ | NPY1R | P25929 | 2/20 | 0.46 |
| ▸ | NPY2R | P49146 | 2/20 | 0.46 |
| ▸ | NPY4R | P50391 | 2/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.46 |
| ▸ | MC4R | P32245 | 1/20 | 0.46 |
| ▸ | CALCR | P30988 | 2/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Talfirastide SCHEMBL15926158 | 0.94 | AGTR1 (0.59) | AGTR1AGTR2EPHA2F2C5AR1 | |
| SCHEMBL30901127 | 0.92 | C5AR1 (0.52) | AGTR1AGTR2EPHA2F2C5AR1 | |
| SCHEMBL8741218 | 0.91 | C5AR1 (0.54) | AGTR1AGTR2EPHA2F2C5AR1 | |
| SCHEMBL29602954 | 0.91 | C5AR1 (0.55) | AGTR1AGTR2C5AR1NTSR2NTSR1 | |
| SCHEMBL29701258 | 0.90 | AGTR2 (0.55) | AGTR1AGTR2EPHA2F2C5AR1 | |
| SCHEMBL30901126 | 0.90 | AGTR1 (0.54) | AGTR1AGTR2EPHA2F2C5AR1 | |
| SCHEMBL9510693 | 0.88 | AGTR1 (0.60) | AGTR1AGTR2EPHA2F2C5AR1 | |
| SCHEMBL29972916 | 0.88 | AGTR1 (0.62) | AGTR1AGTR2EPHA2F2C5AR1 | |
| SCHEMBL15928128 | 0.88 | AGTR2 (0.59) | AGTR1AGTR2F2C5AR1NTSR2 | |
| SCHEMBL7052378 | 0.88 | AGTR2 (0.65) | AGTR1AGTR2EPHA2F2C5AR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4629784-A | ENZYME INHIBITORS; HORMONES; STABILIZERS; | THE UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 1986-12-16 | — | — | US | disclosed |