SCHEMBL30901127

CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](C)N)C(C)C)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N1CCC[C@H]1C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	C5AR1	P21730	2/20	0.52

▸	AGTR1	P30556	4/20	0.52

▸	AGTR2	P50052	2/20	0.52

▸	NTSR1	P30989	6/20	0.50

▸	NTSR2	O95665	5/20	0.50

▸	APLNR	P35414	1/20	0.49

▸	SORT1	Q99523	4/20	0.49

▸	MC4R	P32245	1/20	0.48

▸	EPHA2	P29317	1/20	0.48

▸	F2	P00734	4/20	0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29602954	0.95	C5AR1 (0.55)	C5AR1AGTR1AGTR2NTSR1NTSR2
Talfirastide SCHEMBL15926158	0.94	AGTR1 (0.59)	C5AR1AGTR1AGTR2NTSR1NTSR2
SCHEMBL8741218	0.94	C5AR1 (0.54)	C5AR1AGTR1AGTR2NTSR1NTSR2
SCHEMBL30901126	0.93	AGTR1 (0.54)	C5AR1AGTR1AGTR2NTSR1NTSR2
SCHEMBL34469957	0.93	AGTR1 (0.62)	C5AR1AGTR1AGTR2NTSR1NTSR2
SCHEMBL10924118	0.92	AGTR1 (0.53)	C5AR1AGTR1AGTR2NTSR1NTSR2
SCHEMBL29701258	0.91	AGTR2 (0.55)	C5AR1AGTR1AGTR2NTSR1NTSR2
SCHEMBL11208567	0.90	C5AR1 (0.56)	C5AR1AGTR1AGTR2APLNRMC4R
SCHEMBL29976356	0.89	C5AR1 (0.57)	C5AR1AGTR1AGTR2NTSR1NTSR2
SCHEMBL9510693	0.89	AGTR1 (0.60)	C5AR1AGTR1AGTR2NTSR1NTSR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-4371556-A1	ANGIOTENSIN(1-7) PHARMACEUTICAL COMPOSITIONS FOR INHALATION	Explicat Pharma GmbH (DE)	2024-05-22	—	—	EP	disclosed