Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 8/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.49 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10924549 | 0.87 | KDM4E (0.47) | HPGDSKDM4EALDH1A1NPSR1HTT | |
| SCHEMBL10925507 | 0.86 | JAK2 (0.49) | HPGDSADORA3KDM4EALDH1A1NPSR1 | |
| SCHEMBL10924946 | 0.85 | ALDH1A1 (0.53) | HPGDSKDM4EALDH1A1NPSR1HTT | |
| SCHEMBL11269746 | 0.83 | HPGDS (0.61) | HPGDSADORA3KDM4EALDH1A1NPSR1 | |
| SCHEMBL1969117 | 0.81 | HPGDS (0.59) | HPGDSADORA3KDM4EALDH1A1NPSR1 | |
| SCHEMBL3263722 | 0.80 | HPGDS (0.57) | HPGDSADORA3KDM4EALDH1A1NPSR1 | |
| SCHEMBL17279852 | 0.79 | HPGDS (0.60) | HPGDSADORA3KDM4EALDH1A1NPSR1 | |
| SCHEMBL7460449 | 0.78 | PDE4D (0.52) | HPGDSADORA3KDM4EALDH1A1NPSR1 | |
| SCHEMBL22890174 | 0.77 | PDE4D (0.67) | KDM4EALDH1A1NPSR1HTTRXFP1 | |
| SCHEMBL3847496 | 0.76 | HPGDS (0.60) | HPGDSADORA3KDM4EALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0177242-A2 | Pollen formation inhibiting pyrazoles | ELI LILLY AND COMPANY (US) | 1986-04-09 | — | — | EP | disclosed |