Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.60 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5173650 | 0.87 | PDE4D (0.55) | HPGDSSMN1; SMN2PDE4DADORA3KDM4E | |
| SCHEMBL2200266 | 0.87 | PDE4D (0.58) | HPGDSSMN1; SMN2PDE4DADORA3KDM4E | |
| SCHEMBL1969117 | 0.86 | HPGDS (0.59) | HPGDSSMN1; SMN2ADORA3KDM4EALDH1A1 | |
| SCHEMBL10984267 | 0.85 | HSP90AA1 (0.62) | HPGDSSMN1; SMN2ALDH1A1LMNARAB9A | |
| SCHEMBL3263722 | 0.85 | HPGDS (0.57) | HPGDSSMN1; SMN2ADORA3KDM4EALDH1A1 | |
| SCHEMBL17279852 | 0.83 | HPGDS (0.60) | HPGDSSMN1; SMN2ADORA3KDM4EALDH1A1 | |
| SCHEMBL10924593 | 0.83 | HPGDS (0.56) | HPGDSSMN1; SMN2ADORA3KDM4EALDH1A1 | |
| SCHEMBL7460449 | 0.82 | PDE4D (0.52) | HPGDSSMN1; SMN2PDE4DADORA3KDM4E | |
| SCHEMBL4382163 | 0.81 | RAB9A (0.49) | HPGDSKDM4EALDH1A1LMNARAB9A | |
| SCHEMBL3847496 | 0.81 | HPGDS (0.60) | HPGDSSMN1; SMN2ADORA3KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0019760-B1 | ESTERS OF 3-ARYL-5-METHYL-PYRAZOLE-4-CARBOXYLIC ACID, HERBICIDES CONTAINING THEM, PROCESS FOR THEIR PREPARATION AND THEIR USE | BASF Aktiengesellschaft (DE) | 1982-06-23 | — | — | EP | claimed |
| EP-0019760-A1 | Esters of 3-aryl-5-methyl-pyrazole-4-carboxylic acid, herbicides containing them, process for their preparation and their use | BASF Aktiengesellschaft (DE) | 1980-12-10 | — | — | EP | claimed |