Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | HTR2B | P41595 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | TPMT | P51580 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2355429 | 0.80 | ALDH1A1 (0.50) | ALDH1A1KDM4EHSD17B10L3MBTL1LMNA | |
| SCHEMBL29536407 | 0.80 | ALDH1A1 (0.50) | ALDH1A1KDM4EHSD17B10L3MBTL1LMNA | |
| SCHEMBL8990966 | 0.74 | HTR2A (0.43) | ALDH1A1KDM4EHSD17B10L3MBTL1HPGD | |
| SCHEMBL21567219 | 0.74 | L3MBTL1 (0.41) | ALDH1A1KDM4EHSD17B10L3MBTL1LMNA | |
| SCHEMBL8912546 | 0.73 | L3MBTL1 (0.44) | ALDH1A1KDM4EHSD17B10L3MBTL1LMNA | |
| SCHEMBL5992537 | 0.73 | CYP3A4 (0.52) | ALDH1A1KDM4EHSD17B10L3MBTL1LMNA | |
| SCHEMBL17797225 | 0.73 | L3MBTL1 (0.40) | ALDH1A1KDM4EHSD17B10L3MBTL1LMNA | |
| SCHEMBL11144274 | 0.73 | L3MBTL1 (0.40) | ALDH1A1KDM4EHSD17B10L3MBTL1LMNA | |
| SCHEMBL2094513 | 0.73 | KDM4E (0.44) | ALDH1A1KDM4EHSD17B10L3MBTL1HPGD | |
| SCHEMBL30126262 | 0.73 | TUBB4A (0.42) | ALDH1A1KDM4EHSD17B10L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0064256-B1 | CEPHALOSPORIN DERIVATIVES AND PROCESS FOR THEIR PREPARATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-03-12 | — | — | EP | disclosed |