Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | CES2 | O00748 | 3/20 | 0.47 |
| ▸ | CES1 | P23141 | 3/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7106882 | 0.80 | TDP1 (0.61) | TDP1L3MBTL1LMNACES2CES1 | |
| SCHEMBL8445181 | 0.77 | CES1 (0.60) | TDP1L3MBTL1LMNACES2CES1 | |
| SCHEMBL2417683 | 0.77 | TDP1 (0.56) | TDP1L3MBTL1LMNACES2CES1 | |
| SCHEMBL27618317 | 0.73 | TDP1 (0.52) | TDP1L3MBTL1LMNACES2CES1 | |
| SCHEMBL5833747 | 0.73 | TDP1 (0.52) | TDP1L3MBTL1LMNACES2CES1 | |
| SCHEMBL5274104 | 0.73 | TDP1 (0.52) | TDP1L3MBTL1LMNACES2CES1 | |
| SCHEMBL11377658 | 0.73 | TDP1 (0.52) | TDP1L3MBTL1LMNACES2CES1 | |
| SCHEMBL338162 | 0.73 | TDP1 (0.52) | TDP1L3MBTL1LMNACES2CES1 | |
| SCHEMBL7207824 | 0.73 | TDP1 (0.52) | TDP1L3MBTL1LMNACES2CES1 | |
| SCHEMBL6204248 | 0.72 | CES2 (0.52) | TDP1L3MBTL1LMNACES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0122448-B1 | TETRA-SUBSTITUTED P-BENZOQUINONES, THEIR PREPARATION AND USE | BASF Aktiengesellschaft (DE) | 1986-02-19 | — | — | EP | claimed |