Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | PGR | P06401 | 1/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.52 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | HRH1 | P35367 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | CES2 | O00748 | 4/20 | 0.50 |
| ▸ | CES1 | P23141 | 4/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA3 | P07451 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA6 | P23280 | 1/20 | 0.48 |
| ▸ | CA5A | P35218 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1397470 | 0.80 | KMT2A (0.58) | TDP1L3MBTL1PGRADRA2AADRA2B | |
| SCHEMBL28283115 | 0.80 | TDP1 (0.56) | TDP1L3MBTL1PGRADRA2AADRA2B | |
| SCHEMBL13039632 | 0.80 | LMNA (0.56) | TDP1L3MBTL1PGRADRA2AADRA2B | |
| SCHEMBL163939 | 0.80 | TDP1 (0.56) | TDP1L3MBTL1PGRADRA2AADRA2B | |
| SCHEMBL8445181 | 0.80 | CES1 (0.60) | TDP1L3MBTL1PGRADRA2AADRA2B | |
| SCHEMBL2417683 | 0.80 | TDP1 (0.56) | TDP1L3MBTL1PGRADRA2AADRA2B | |
| SCHEMBL28808147 | 0.79 | ALDH1A1 (0.52) | TDP1ADRA2BLMNACES2CES1 | |
| SCHEMBL27003 | 0.78 | LMNA (0.58) | TDP1L3MBTL1PGRADRA2AADRA2B | |
| SCHEMBL15834920 | 0.78 | LMNA (0.55) | TDP1L3MBTL1PGRADRA2AADRA2B | |
| SCHEMBL12251084 | 0.78 | LMNA (0.55) | TDP1L3MBTL1PGRADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7049459-B2 | 1-[(4-methyl thio)phenyl]-2-(phenyl acetoxy)-1-ethanone and a process for preparing the same | SHASUN CHEMICALS AND DRUGS LIMITED (IN) | 2006-05-23 | — | — | US | claimed |
| US-20040242680-A1 | 1-[(4-methyl thio)phenyl]-2-(phenyl acetoxy)-1-ethanone and a process for preparing the same | SHASUN CHEMICALS AND DRUGS LIMITED (IN) | 2004-12-02 | — | — | US | claimed |
| WO-2003030812-A2 | 1-[(4-METHYL THIO)PHENYL]-2-(PHENYL ACETOXY)-1-ETHANONE AND A PROCESS FOR PREPARING THE SAME | SHASUN CHEMICALS AND DRUGS LIMITED (IN) | 2003-04-17 | — | — | WO | claimed |
| CN-118420560-A | Synthesis method of 2- (trifluoromethyl) -4, 5-disubstituted thiazole compound | 西北师范大学 | 2024-08-02 | — | — | CN | disclosed |
| US-11046670-B2 | Piperazinyl norbenzomorphan compounds and methods for using the same | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2021-06-29 | — | — | US | disclosed |
| US-20210009551-A1 | COMPOUNDS AND METHODS FOR TREATING FIBROSIS OR CANCER | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2021-01-14 | — | — | US | disclosed |
| WO-2020004408-A1 | COMPOSITION, CURED PRODUCT, PATTERN-FORMING METHOD, COMPOUND, POLYMER, AND METHOD FOR PRODUCING COMPOUND | 東京応化工業株式会社 | 2020-01-02 | — | — | WO | disclosed |
| US-20190077789-A1 | PIPERAZINYL NORBENZOMORPHAN COMPOUNDS AND METHODS FOR USING THE SAME | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2019-03-14 | — | — | US | disclosed |
| CN-1140267-C | Compositions for a once a day treatment of cyclooxygenase-2 mediated diseases | — | 2004-03-03 | — | — | CN | disclosed |
| CN-1225010-A | Compositions for a once a day treatment of cyclooxygenase-2 mediated diseases | MERCK & CO INC (US) | 1999-08-04 | — | — | CN | disclosed |
| EP-0019450-B1 | PYRIMIDINE DERIVATIVES AND THEIR PRODUCTION AND AGRICULTURAL USES | Takeda Chemical Industries, Ltd. (JP) | 1983-02-23 | — | — | EP | disclosed |
| EP-0019450-A1 | Pyrimidine derivatives and their production and agricultural uses | Takeda Chemical Industries, Ltd. (JP) | 1980-11-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040242680-A1 | 1-[(4-methyl thio)phenyl]-2-(phenyl acetoxy)-1-ethanone and a process for preparing the same | PTGES2, PTGS2, CYP2J2 | TDP1 2396/4885L3MBTL1 4572/4885PGR 2152/4885 |
| US-20190077789-A1 | PIPERAZINYL NORBENZOMORPHAN COMPOUNDS AND METHODS FOR USING THE SAME | GAP43, NCDN, NLN | TDP1 2879/4885L3MBTL1 502/4885PGR 882/4885 |
| US-11046670-B2 | Piperazinyl norbenzomorphan compounds and methods for using the same | GAP43, NCDN, NLN | TDP1 2879/4885L3MBTL1 502/4885PGR 882/4885 |
| US-20210009551-A1 | COMPOUNDS AND METHODS FOR TREATING FIBROSIS OR CANCER | MMP1, MMP8, SERPINB1 | TDP1 3617/4885L3MBTL1 1021/4885PGR 2051/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.