Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.36 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.36 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | F7 | P08709 | 2/20 | 0.35 |
| ▸ | F3 | P13726 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11034809 | 0.85 | LMNA (0.48) | TK1LMNASMN1; SMN2HIF1AEPAS1 | |
| SCHEMBL10719251 | 0.85 | EPHX2 (0.47) | LMNAKDM4EALDH1A1MAPTTDP1 | |
| SCHEMBL10719255 | 0.85 | EPHX2 (0.47) | LMNAKDM4EALDH1A1MAPTTDP1 | |
| SCHEMBL11397970 | 0.82 | SMN1; SMN2 (0.51) | TK1LMNASMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL10504842 | 0.82 | ALDH1A1 (0.54) | TK1LMNAKDM4ECYP1A2GRIA1 | |
| SCHEMBL10504844 | 0.82 | ALDH1A1 (0.54) | TK1LMNAKDM4ECYP1A2GRIA1 | |
| SCHEMBL11399957 | 0.81 | SMN1; SMN2 (0.52) | TK1LMNASMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL10506071 | 0.80 | LMNA (0.54) | TK1LMNAKDM4ECYP1A2GRIA1 | |
| SCHEMBL10506077 | 0.80 | LMNA (0.54) | TK1LMNAKDM4ECYP1A2GRIA1 | |
| SCHEMBL10752190 | 0.78 | LMNA (0.56) | TK1LMNAKDM4ECYP1A2GRIA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-60087272-A | — | — | None | — | — | JP | disclosed |
| JP-S6087272-A | 5-FLUOROURACIL DERIVATIVE AND BLOOD PLATELET COAGULATION INHIBITOR CONTAINING THE SAME | TERUMO CORP | 1985-05-16 | — | — | JP | disclosed |