Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TK1 | P04183 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | MGLL | Q99685 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.39 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10928811 | 0.85 | TK1 (0.44) | LMNATK1KMT2AMAPTCYP1A2 | |
| SCHEMBL10752190 | 0.85 | LMNA (0.56) | LMNATK1KMT2AMAPTCYP1A2 | |
| SCHEMBL10504842 | 0.82 | ALDH1A1 (0.54) | LMNATK1KMT2AMAPTCYP1A2 | |
| SCHEMBL10504844 | 0.82 | ALDH1A1 (0.54) | LMNATK1KMT2AMAPTCYP1A2 | |
| SCHEMBL6760088 | 0.81 | CYP1A2 (0.62) | LMNATK1KMT2AMAPTCYP2C9 | |
| SCHEMBL17232952 | 0.80 | LMNA (0.47) | LMNATK1KMT2AMAPTCYP2C9 | |
| SCHEMBL10976239 | 0.79 | CYP1A2 (0.60) | LMNATK1KMT2AMAPTCYP2C9 | |
| SCHEMBL10506071 | 0.79 | LMNA (0.54) | LMNATK1KMT2AMAPTCYP1A2 | |
| SCHEMBL10506077 | 0.79 | LMNA (0.54) | LMNATK1KMT2AMAPTCYP1A2 | |
| SCHEMBL10754597 | 0.79 | ALDH1A1 (0.45) | LMNATK1KMT2AMAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-59067275-A | — | — | None | — | — | JP | disclosed |
| JP-S5967275-A | 5-FLUOROURACIL DERIVATIVE AND ITS PREPARATION | TERUMO CORP | 1984-04-16 | — | — | JP | disclosed |