Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | F7 | P08709 | 2/20 | 0.41 |
| ▸ | F3 | P13726 | 2/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | TK1 | P04183 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10504844 | 0.90 | ALDH1A1 (0.54) | LMNAALDH1A1CYP3A4ALOX15HSD17B10 | |
| SCHEMBL10504842 | 0.90 | ALDH1A1 (0.54) | LMNAALDH1A1CYP3A4ALOX15HSD17B10 | |
| SCHEMBL10506077 | 0.85 | LMNA (0.54) | LMNAALDH1A1CYP3A4ALOX15HSD17B10 | |
| SCHEMBL10506071 | 0.85 | LMNA (0.54) | LMNAALDH1A1CYP3A4ALOX15HSD17B10 | |
| SCHEMBL11034809 | 0.85 | LMNA (0.48) | LMNAALDH1A1CYP3A4ALOX15HSD17B10 | |
| SCHEMBL10754597 | 0.84 | ALDH1A1 (0.45) | LMNAALDH1A1CYP3A4ALOX15HSD17B10 | |
| SCHEMBL10505497 | 0.81 | LMNA (0.56) | LMNAALDH1A1CYP3A4ALOX15HSD17B10 | |
| SCHEMBL10505500 | 0.81 | LMNA (0.56) | LMNAALDH1A1CYP3A4ALOX15HSD17B10 | |
| SCHEMBL10750606 | 0.79 | SMN1; SMN2 (0.48) | LMNAALDH1A1CYP3A4ALOX15HSD17B10 | |
| SCHEMBL10928811 | 0.78 | TK1 (0.44) | LMNAALDH1A1CYP3A4ALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0222155-A1 | 5-Fluorouracil derivatives | TERUMO KABUSHIKI KAISHA trading as TERUMO CORPORATION (JP) | 1987-05-20 | — | — | EP | disclosed |