(Chloromethyl)Benzene

(Chloromethyl)Benzene

SCHEMBL10929432

C1COCCN1.ClCc1ccccc1

nearest known ligand 0.46

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 4/20 0.46
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
CYP2C9 P11712 2/20 0.42
KDM4E B2RXH2 1/20 0.42
GAA P10253 1/20 0.42
GBA1 P04062 1/20 0.41
ALDH1A1 P00352 1/20 0.39
TSHR P16473 1/20 0.39
CYP2C19 P33261 1/20 0.39
HIF1A Q16665 1/20 0.39
HTR2C P28335 7/20 0.38
HTR2B P41595 2/20 0.38
HTR2A P28223 2/20 0.37
HTR3A P46098 2/20 0.37
CHRM4 P08173 1/20 0.37
CHRM5 P08912 1/20 0.37
CHRM1 P11229 1/20 0.37
CHRM3 P20309 1/20 0.37
HTR6 P50406 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
(Chloromethyl)Benzene SCHEMBL27762297 0.81 FKBP1A (0.41) SIGMAR1MEN1KMT2AALDH1A1TSHR
Benzylamine SCHEMBL8413972 0.80 LOXL2 (0.56) SIGMAR1MEN1KMT2ACYP2C9KDM4E
(Chloromethyl)Benzene SCHEMBL9002178 0.79 FKBP1A (0.40) SIGMAR1MEN1KMT2AKDM4EALDH1A1
SCHEMBL10918817 0.78 SIGMAR1 (0.68) SIGMAR1MEN1KMT2ACYP2C9KDM4E
(Chloromethyl)Benzene SCHEMBL28231553 0.78 CALM1 (0.50) SIGMAR1ALDH1A1TSHRHTR2A
(Chloromethyl)Benzene SCHEMBL27708420 0.78
(Chloromethyl)Benzene SCHEMBL2562673 0.78
Phenylacetaldehyde SCHEMBL28295710 0.77 MAOB (0.40) SIGMAR1MEN1KMT2ACYP2C9KDM4E
(Chloromethyl)Benzene SCHEMBL27782249 0.77 SIGMAR1 (0.45) SIGMAR1MEN1KMT2ACYP2C9GBA1
SCHEMBL17526418 0.77 SIGMAR1 (0.66) SIGMAR1MEN1KMT2ACYP2C9KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4511480-A Corrosion inhibition in deep gas wells by phosphate esters of poly-oxyalkylated thiols PETROLITE CORPORATION (US) 1985-04-16 US disclosed