Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 11/20 | 0.69 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.63 |
| ▸ | HTR1A | P08908 | 1/20 | 0.61 |
| ▸ | DRD2 | P14416 | 1/20 | 0.61 |
| ▸ | CCR3 | P51677 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11399131 | 0.93 | SIGMAR1 (0.81) | SIGMAR1CCR3 | |
| SCHEMBL10685564 | 0.88 | SIGMAR1 (0.80) | SIGMAR1SLC6A3HTR1ADRD2CCR3 | |
| Hydrochloric Acid SCHEMBL11076651 | 0.86 | SIGMAR1 (0.77) | SIGMAR1SLC6A3HTR1ADRD2CCR3 | |
| SCHEMBL6056974 | 0.86 | SLC6A3 (0.83) | SIGMAR1SLC6A3HTR1ADRD2CCR3 | |
| SCHEMBL7264546 | 0.86 | SLC6A3 (0.83) | SIGMAR1SLC6A3HTR1ADRD2CCR3 | |
| SCHEMBL14407778 | 0.86 | SLC6A3 (0.83) | SIGMAR1SLC6A3HTR1ADRD2CCR3 | |
| SCHEMBL13150782 | 0.86 | SLC6A3 (0.83) | SIGMAR1SLC6A3HTR1ADRD2CCR3 | |
| SCHEMBL6583768 | 0.85 | CCR3 (0.69) | SIGMAR1CCR3 | |
| SCHEMBL7329630 | 0.85 | SIGMAR1 (0.81) | SIGMAR1CCR3 | |
| Hydrochloric Acid SCHEMBL10502673 | 0.85 | SIGMAR1 (0.74) | SIGMAR1SLC6A3HTR1ADRD2CCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-60152478-A | — | — | None | — | — | JP | disclosed |
| JP-S60152478-A | PIPERAZINE DERIVATIVE | SHOWA DENKO KK | 1985-08-10 | — | — | JP | disclosed |