Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 12/20 | 0.81 |
| ▸ | CCR3 | P51677 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | LTA4H | P09960 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11399131 | 0.93 | SIGMAR1 (0.81) | SIGMAR1CCR3POLBLTA4H | |
| SCHEMBL2962629 | 0.90 | SIGMAR1 (1.00) | SIGMAR1CCR3POLBLTA4H | |
| SCHEMBL6550825 | 0.90 | SIGMAR1 (1.00) | SIGMAR1CCR3POLBLTA4H | |
| SCHEMBL10932016 | 0.85 | SIGMAR1 (0.69) | SIGMAR1CCR3 | |
| SCHEMBL3593088 | 0.83 | SIGMAR1 (0.89) | SIGMAR1CCR3POLBLTA4H | |
| SCHEMBL11801794 | 0.83 | CCR3 (0.89) | SIGMAR1CCR3 | |
| SCHEMBL5302082 | 0.82 | LTA4H (0.86) | SIGMAR1CCR3POLBLTA4H | |
| SCHEMBL8092982 | 0.82 | SIGMAR1 (0.85) | SIGMAR1CCR3TSHR | |
| SCHEMBL14100161 | 0.82 | SIGMAR1 (0.69) | SIGMAR1LTA4H | |
| SCHEMBL14824971 | 0.81 | SIGMAR1 (0.81) | SIGMAR1CCR3POLBLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025058989-A1 | NOVEL COMPOUNDS FOR TREATING CANCER | MARSAL THERAPEUTICS, INC. (US) | 2025-03-20 | — | — | WO | disclosed |
| US-5177077-A | Inhibitors at dopamine uptake sites, treatment of mental disorders | NOVO NORDISK A/S (DK) | 1993-01-05 | — | — | US | disclosed |
| WO-1992001686-A1 | 1,4-DISUBSTITUTED PIPERAZINES | NOVO NORDISK A/S (DK) | 1992-02-06 | — | — | WO | disclosed |
| US-4265894-A | TREATING PARKINSON'S DISEASE AND ACROMEGALY | GIST BROCADES, N.V. (NL) | 1981-05-05 | — | — | US | disclosed |
| US-4202896-A | DOPAMINERGIC ACTIVITY | GIST-BROCADES N.V. (NL) | 1980-05-13 | — | — | US | disclosed |