SCHEMBL10933428

SCHEMBL10933428

Cc1ccc(N(C)C)c(C(c2c(N(C)C)ccc(C)c2C)c2c(N(C)C)ccc(C)c2C)c1C

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.32
KMT2A Q03164 1/20 0.32
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL392464 0.75 GAA (0.33) GAAKMT2AMAPT
SCHEMBL9814882 0.71 CHEK1 (0.31) GAAKMT2AMAPT
SCHEMBL27649636 0.70 CHEK1 (0.30) GAAMAPT
SCHEMBL10933423 0.65 CHEK1 (0.30) GAAMAPT
SCHEMBL533038 0.65 POLB (0.52) GAAKMT2AMAPT
SCHEMBL11645323 0.65 ALDH1A1 (0.40) GAAMAPT
SCHEMBL11789041 0.64 CHEK1 (0.32) GAAKMT2AMAPT
SCHEMBL30733276 0.64 MAPT (0.48) GAAKMT2AMAPT
SCHEMBL1911943 0.64 MAPT (0.48) GAAKMT2AMAPT
SCHEMBL13385342 0.62 MAPT (0.41) GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0047184-B1 RADIATION POLYMERIZABLE COMPOSITION FOR FORMING HEAT-RESISTANT RELIEF STRUCTURES ON ELECTRICAL DEVICES SUCH AS SEMICONDUCTORS AND CAPACITORS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1985-01-09 EP disclosed
EP-0047184-A2 Radiation polymerizable composition for forming heat-resistant relief structures on electrical devices such as semiconductors and capacitors E.I. DU PONT DE NEMOURS AND COMPANY (US) 1982-03-10 EP disclosed