Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 2/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8734640 | 0.87 | PKM (0.48) | PTGS2LMNACA12CA1CA2 | |
| SCHEMBL10965241 | 0.80 | ALDH1A1 (0.34) | APPCYP3A4KDM4EALDH1A1TP53 | |
| SCHEMBL14394423 | 0.80 | ABL1 (0.47) | PTGS2LMNACA12CA1CA2 | |
| SCHEMBL7461096 | 0.78 | GAA (0.40) | PTGS2LMNACA12CA1CA2 | |
| SCHEMBL26292501 | 0.74 | KDM4E (0.46) | PTGS2LMNACA12CA1CA2 | |
| SCHEMBL30158577 | 0.72 | GAA (0.41) | LMNACA1CA2PKMMAPT | |
| SCHEMBL2097204 | 0.72 | ACHE (0.54) | PTGS2CA9MAPTKMT2ACYP3A4 | |
| SCHEMBL23033431 | 0.71 | APP (0.53) | LMNACA12CA1CA2CA7 | |
| Hydrochloric Acid SCHEMBL28007508 | 0.70 | ACHE (0.52) | PTGS2CA9MAPTKMT2ACYP3A4 | |
| SCHEMBL1156251 | 0.69 | MAOB (0.57) | LMNACA2KMT2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4517005-A | Aminophenol urease inhibitors and urease inhibited urea based fertilizer compositions | ALLIED CORPORATION (US) | 1985-05-14 | — | — | US | disclosed |