Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2002815 | 0.81 | PKM (0.52) | GAAMAPTTSHRMAPK1HTT | |
| SCHEMBL14394423 | 0.78 | ABL1 (0.47) | GAAMAPTMAPK1PTGS2CA12 | |
| SCHEMBL10933696 | 0.78 | PTGS2 (0.38) | GAAMAPTMAPK1PTGS2CA12 | |
| SCHEMBL13963710 | 0.77 | PTGS2 (0.50) | GAAMAPTTSHRMAPK1HTT | |
| SCHEMBL26097042 | 0.77 | MAPT (0.44) | GAAMAPTTSHRMAPK1HTT | |
| SCHEMBL11016393 | 0.74 | ALDH1A1 (0.40) | GAAMAPTTSHRHTTCA1 | |
| SCHEMBL11330721 | 0.74 | EGFR (0.46) | GAAMAPTTSHRMAPK1HTT | |
| SCHEMBL11344842 | 0.72 | MAPT (0.52) | GAAMAPTTSHRMAPK1HTT | |
| SCHEMBL1438002 | 0.72 | THRB (0.60) | GAAMAPTPTGS2CA12CA1 | |
| SCHEMBL7105484 | 0.72 | MAPT (0.57) | GAAMAPTTSHRMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1231889-A2 | DIRECT HAIR DYES AND USE THEREOF | Henkel Kommanditgesellschaft auf Aktien (DE) | 2002-08-21 | — | — | EP | disclosed |
| EP-1169012-A1 | COLORANTS CONTAINING 4-AMINO-2-AMINOMETHYL-PHENOL DERIVATIVES AND THEIR USE FOR COLORING KERATIN FIBERS | Henkel Kommanditgesellschaft auf Aktien (DE) | 2002-01-09 | — | — | EP | disclosed |
| WO-2001026615-A2 | DIRECT HAIR DYES CONTAINING A HYDROXYANTHROQUINONE DERIVATIVE | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2001-04-19 | — | — | WO | disclosed |
| WO-2000061088-A1 | COLORANTS CONTAINING 4-AMINO-2-AMINOMETHYL-PHENOL DERIVATIVES AND THEIR USE FOR COLORING KERATIN FIBERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2000-10-19 | — | — | WO | disclosed |