Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 2/20 | 0.43 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.43 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.43 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TK1 | P04183 | 2/20 | 0.34 |
| ▸ | CTSG | P08311 | 2/20 | 0.34 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.34 |
| ▸ | CMA1 | P23946 | 2/20 | 0.34 |
| ▸ | DUT | P33316 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10796999 | 1.00 | PLA2G2A (0.43) | PLA2G2APLA2G10PLA2G1BPLA2G5KIF11 | |
| SCHEMBL10796866 | 0.87 | PLA2G2A (0.44) | PLA2G2APLA2G10PLA2G1BPLA2G5KIF11 | |
| SCHEMBL10796580 | 0.87 | PLA2G2A (0.44) | PLA2G2APLA2G10PLA2G1BPLA2G5KIF11 | |
| SCHEMBL6700873 | 0.86 | PRKD3 (0.48) | PLA2G2APLA2G10PLA2G1BPLA2G5KIF11 | |
| SCHEMBL8638519 | 0.86 | PRKD3 (0.48) | PLA2G2APLA2G10PLA2G1BPLA2G5KIF11 | |
| SCHEMBL8911994 | 0.85 | PLA2G2A (0.38) | PLA2G2APLA2G10PLA2G1BPLA2G5KIF11 | |
| SCHEMBL10940286 | 0.84 | ALDH1A1 (0.41) | PLA2G2APLA2G10PLA2G1BPLA2G5PRSS1 | |
| SCHEMBL25764010 | 0.83 | PLA2G2A (0.42) | PLA2G2APLA2G10PLA2G1BPLA2G5CSNK1E | |
| SCHEMBL28048301 | 0.81 | PLA2G2A (0.39) | PLA2G2APLA2G10PLA2G1BPLA2G5KIF11 | |
| SCHEMBL18651709 | 0.81 | KIF11 (0.43) | PLA2G2APLA2G10PLA2G1BPLA2G5KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4562179-A | ANTITUMOR AND ANTICARCINOGENIC AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-12-31 | — | — | US | disclosed |