Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 9/20 | 0.66 |
| ▸ | ADRA2B | P18089 | 7/20 | 0.66 |
| ▸ | ADRA1A | P35348 | 15/20 | 0.62 |
| ▸ | ADRA1D | P25100 | 14/20 | 0.62 |
| ▸ | ADRA1B | P35368 | 13/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 8/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10742586 | 0.99 | ADRA2C (0.64) | ADRA2CADRA2BADRA1AADRA1DADRA1B | |
| Hydrochloric Acid SCHEMBL9654070 | 0.77 | ADRA2C (0.65) | ADRA2CADRA2BADRA1AADRA1DADRA1B | |
| SCHEMBL15378775 | 0.76 | MAOA (0.57) | ADRA2CADRA2BADRA1AADRA1DADRA1B | |
| SCHEMBL11008145 | 0.75 | ADRA2C (0.63) | ADRA2CADRA2BADRA1AADRA1DADRA1B | |
| SCHEMBL6366434 | 0.75 | ADRA2B (0.79) | ADRA2CADRA2BADRA1AADRA1DADRA1B | |
| SCHEMBL10965109 | 0.74 | ADRA2C (0.78) | ADRA2CADRA2BADRA1AADRA1DADRA1B | |
| SCHEMBL11227694 | 0.74 | ADRA2C (0.69) | ADRA2CADRA2BADRA1AADRA1DADRA1B | |
| Hydrochloric Acid SCHEMBL10743273 | 0.74 | ADRA2C (0.61) | ADRA2CADRA2BADRA1AADRA1DADRA1B | |
| SCHEMBL11163458 | 0.74 | NISCH (0.68) | ADRA2CADRA2BADRA1AADRA1DADRA1B | |
| Hydrochloric Acid SCHEMBL11164250 | 0.73 | NISCH (0.66) | ADRA2CADRA2BADRA1AADRA1DADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1985000366-A1 | NEW AMIDINES, PREPARATION PROCESS AND THERAPEUTICAL APPLICATION THEREOF | LABORATOIRES CHAUVIN-BLACHE (FR) | 1985-01-31 | — | — | WO | disclosed |
| EP-0132190-A1 | Amidines, process for their preparation and their therapeutical use | LABORATOIRES CHAUVIN S.A. (FR) | 1985-01-23 | — | — | EP | disclosed |