Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 13/20 | 0.69 |
| ▸ | ADRA2B | P18089 | 11/20 | 0.69 |
| ▸ | ADRA1D | P25100 | 16/20 | 0.67 |
| ▸ | ADRA1A | P35348 | 16/20 | 0.67 |
| ▸ | ADRA1B | P35368 | 14/20 | 0.67 |
| ▸ | ADRA2A | P08913 | 11/20 | 0.67 |
| ▸ | MAOA | P21397 | 2/20 | 0.51 |
| ▸ | MAOB | P27338 | 2/20 | 0.51 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11233332 | 0.83 | ADRA1A (0.61) | ADRA2CADRA2BADRA1DADRA1AADRA1B | |
| SCHEMBL11231308 | 0.82 | ADRA2C (1.00) | ADRA2CADRA2BADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL11227435 | 0.81 | ADRA2C (0.97) | ADRA2CADRA2BADRA1DADRA1AADRA1B | |
| SCHEMBL3173010 | 0.78 | MAOA (0.71) | ADRA2CADRA2BADRA1DADRA1AADRA1B | |
| SCHEMBL6366946 | 0.78 | ADRA1A (1.00) | ADRA2CADRA2BADRA1DADRA1AADRA1B | |
| SCHEMBL3169152 | 0.77 | MAOA (0.68) | ADRA2CADRA2BADRA1DADRA1AADRA1B | |
| SCHEMBL4209729 | 0.77 | ADRA2C (0.78) | ADRA2CADRA2BADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL9652264 | 0.76 | ADRA2C (0.60) | ADRA2CADRA2BADRA1DADRA1AADRA1B | |
| SCHEMBL6366979 | 0.76 | ADRA1A (0.72) | ADRA2CADRA2BADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL9654151 | 0.75 | ADRA2C (0.76) | ADRA2CADRA2BADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4343810-A | Method of inhibiting sickling of sickle erythrocytes using 2-((haloanilino)methyl)-2-imidazolines | THE DOW CHEMICAL COMPANY (US) | 1982-08-10 | — | — | US | claimed |
| US-4343810-A | Method of inhibiting sickling of sickle erythrocytes using 2-((haloanilino)methyl)-2-imidazolines | THE DOW CHEMICAL COMPANY (US) | 1982-08-10 | — | — | US | disclosed |