SCHEMBL10934591

SCHEMBL10934591

CS(=O)(=O)Nc1cccc2ccc(S(=O)(=O)O)cc12

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 2/20 0.61
CASP6 P55212 2/20 0.52
GLO1 Q04760 2/20 0.47
MMP2 P08253 1/20 0.46
NQO2 P16083 2/20 0.45
MTNR1A P48039 2/20 0.45
MTNR1B P49286 2/20 0.45
HTT P42858 2/20 0.44
ALOX15 P16050 1/20 0.44
NR3C1 P04150 1/20 0.44
PGR P06401 1/20 0.44
NR3C2 P08235 1/20 0.44
AR P10275 1/20 0.44
HSD17B10 Q99714 2/20 0.43
KDM4E B2RXH2 1/20 0.43
HPGD P15428 1/20 0.43
ALDH1A1 P00352 2/20 0.43
EP300 Q09472 1/20 0.43
KAT2B Q92831 1/20 0.43
KAT8 Q9H7Z6 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL140691 0.88 CASP6 (0.68) KEAP1CASP6GLO1MMP2HTT
SCHEMBL17000439 0.86 CASP6 (0.56) KEAP1CASP6NQO2MTNR1AMTNR1B
SCHEMBL9351736 0.81 KEAP1 (0.65) KEAP1GLO1MMP2MTNR1AMTNR1B
SCHEMBL18268221 0.81 CASP6 (0.51) KEAP1CASP6MMP2NQO2MTNR1A
SCHEMBL4102145 0.81 CASP6 (0.79) CASP6NQO2MTNR1AMTNR1BKDM4E
SCHEMBL11515311 0.79 CASP6 (0.50) KEAP1CASP6MMP2NQO2MTNR1A
SCHEMBL4103361 0.79 CASP6 (0.77) CASP6NQO2MTNR1AMTNR1BKDM4E
SCHEMBL2293946 0.78 CASP6 (0.49) CASP6NQO2MTNR1AMTNR1BHTT
SCHEMBL9130869 0.78 SNCA (0.61) CASP6ALOX15HSD17B10KDM4EHPGD
SCHEMBL26885979 0.77 CASP6 (0.58) CASP6NQO2MTNR1AMTNR1BHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0049003-B1 DYE-DIFFUSION TRANSFER PROCESS AGFA-GEVAERT N.V. (BE) 1985-09-18 EP disclosed
EP-0049002-B1 PROCESS FOR THE PRODUCTION OF A MULTICOLOUR IMAGE BY IMAGE-WISE DYE DIFFUSION TRANSFER AGFA-GEVAERT N.V. (BE) 1985-09-18 EP disclosed
EP-0038092-B1 PHOTOGRAPHIC MATERIAL SUITED FOR USE IN DIFFUSION TRANSFER PHOTOGRAPHY AGFA-GEVAERT N.V. (BE) 1984-03-07 EP disclosed
US-4396699-A SILVER HALIDE SOLVENT IN ALKALINE PROCESSING LIQUID AGFA-GEVAERT, N.V. (BE) 1983-08-02 US disclosed
US-4371604-A Photographic material suited for use in diffusion transfer photography AGFA-GEVAERT, N.V. (BE) 1983-02-01 US disclosed
US-4353975-A DEVELOPER CONTAINING TRIISOPROPANOLAMINE; IMPROVED DYE DENSITY AGFA-GEVAERT, N.V. (BE) 1982-10-12 US disclosed
EP-0049003-A1 Dye-diffusion transfer process AGFA-GEVAERT N.V. (BE) 1982-04-07 EP disclosed
EP-0049002-A1 Process for the production of a multicolour image by image-wise dye diffusion transfer AGFA-GEVAERT N.V. (BE) 1982-04-07 EP disclosed
EP-0038092-A1 Photographic material suited for use in diffusion transfer photography AGFA-GEVAERT N.V. (BE) 1981-10-21 EP disclosed