SCHEMBL9351736

SCHEMBL9351736

CS(=O)(=O)Nc1cccc2ccc(O)cc12

nearest known ligand 0.65

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 1/20 0.65
TRPV1 Q8NER1 13/20 0.51
KDM4E B2RXH2 1/20 0.50
MEN1 O00255 1/20 0.50
MAPT P10636 1/20 0.50
RAB9A P51151 1/20 0.50
KMT2A Q03164 1/20 0.50
MTNR1A P48039 1/20 0.50
MTNR1B P49286 1/20 0.50
GLO1 Q04760 1/20 0.49
EP300 Q09472 1/20 0.49
KAT2B Q92831 1/20 0.49
KAT8 Q9H7Z6 1/20 0.49
MMP2 P08253 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11019096 0.84 TRPV1 (0.49) KEAP1TRPV1KDM4EMEN1MAPT
SCHEMBL4649512 0.84 TRPV1 (0.50) TRPV1KDM4EMEN1MAPTRAB9A
SCHEMBL1413142 0.83 MCL1 (0.50) TRPV1KDM4EMEN1MAPTRAB9A
SCHEMBL11312447 0.82 KEAP1 (0.48) KEAP1TRPV1KDM4EMEN1MAPT
SCHEMBL10934591 0.81 KEAP1 (0.61) KEAP1KDM4EMEN1MAPTKMT2A
SCHEMBL6583801 0.81 TRPV1 (0.54) TRPV1KDM4EMEN1MAPTRAB9A
SCHEMBL808090 0.80 HKDC1 (0.61) KEAP1TRPV1MEN1MAPTKMT2A
SCHEMBL2124660 0.79 KEAP1 (1.00) KEAP1KDM4EMEN1MAPTKMT2A
SCHEMBL7095286 0.78 KDM4E (0.51) TRPV1KDM4EMEN1MAPTRAB9A
SCHEMBL16187949 0.78 KMT2A (0.60) KEAP1TRPV1MEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0260561-B1 PROCESS FOR DYEING LEATHER WITH DYESTUFF MIXTURES BAYER AG (DE) 1993-03-17 EP claimed
EP-0260561-A2 Process for dyeing leather with dyestuff mixtures BAYER AG (DE) 1988-03-23 EP claimed
EP-0384893-B1 Process for the preparation of asymmetrical 1,2-metal complex dyestuffs CIBA GEIGY AG (CH) 1994-09-07 EP disclosed
US-5229502-A PREPARATION OF 1:2 CHROMIUM COMPLEXES ONE SULFO SUBSTITUTED AND ONE SULFONAMIDO OR THE LIKE SUBSTITUTED AZO DYES CIBA-GEIGY CORPORATION (US) 1993-07-20 US disclosed
EP-0260561-B1 PROCESS FOR DYEING LEATHER WITH DYESTUFF MIXTURES BAYER AG (DE) 1993-03-17 EP disclosed
EP-0260557-B1 ASYMMETRIC 1:2 METAL COMPLEX DYESTUFS BAYER AG (DE) 1991-11-27 EP disclosed
EP-0384893-A1 Process for the preparation of asymmetrical 1,2-metal complex dyestuffs CIBA-GEIGY AG (CH) 1990-08-29 EP disclosed
EP-0260557-A2 Asymmetric 1:2 metal complex dyestufs BAYER AG (DE) 1988-03-23 EP disclosed
EP-0088930-B1 TRIAZOLE-TRIAZINYL AZO DYES BAYER AG (DE) 1986-04-09 EP disclosed
EP-0066230-B1 1:2-ASYMMETRIC DYESTUFFS OF CHROMIUM BAYER AG (DE) 1986-03-05 EP disclosed
US-4556707-A DYEING CELLULOSE FIBERS AND POLYAMIDE FIBERS BAYER AKTIENGESELLSCHAFT (DE) 1985-12-03 US disclosed
EP-0024609-B1 PROCESS FOR THE PREPARATION OF CONCENTRATED SOLUTIONS OF METAL COMPLEX DYESTUFFS FREE FROM SULFONIC GROUPS BAYER AG (DE) 1983-01-12 EP disclosed
US-4354968-A Azo reactive dyestuffs having an aryl-triazinyl-aryl diazo component BAYER AKTIENGESELLSCHAFT (DE) 1982-10-19 US disclosed
EP-0013879-B1 REACTIVE DYESTUFFS, THEIR PREPARATION AND THEIR USE FOR DYEING MATERIALS CONTAINING HYDROXYL OR AMIDE GROUPS BAYER AG (DE) 1982-09-15 EP disclosed
EP-0024609-A1 Process for the preparation of concentrated solutions of metal complex dyestuffs free from sulfonic groups BAYER AG (DE) 1981-03-11 EP disclosed
US-4219473-A Substituted unsymmetrical azo, azomethine 1:2 chromium complexes CIBA-GEIGY CORPORATION (US) 1980-08-26 US disclosed
EP-0013879-A1 Reactive dyestuffs, their preparation and their use for dyeing materials containing hydroxyl or amide groups BAYER AG (DE) 1980-08-06 EP disclosed
US-4053462-A UNSYMMETRICAL PHENYL AZO NAPHTHYL CHROMIUM COMPLEX DYES CIBA-GEIGY CORPORATION (US) 1977-10-11 US disclosed
US-4005065-A GOOD FASTNESS TO LIGHT, PERSPIRATION, FULLING, DECATIZING AND CARBONIZING CIBA-GEIGY CORPORATION (US) 1977-01-25 US disclosed
US-3966703-A Asymmetrical frisazo dyestuffs derived from diazotized 2,7-diamino-carbazole BAYER AKTIENGESELLSCHAFT (DT) 1976-06-29 US disclosed