Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | CTSL | P07711 | 1/20 | 0.55 |
| ▸ | CTSB | P07858 | 1/20 | 0.55 |
| ▸ | CTSS | P25774 | 1/20 | 0.55 |
| ▸ | CTSK | P43235 | 1/20 | 0.55 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.53 |
| ▸ | TACR1 | P25103 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11211146 | 0.96 | TSHR (0.57) | ALDH1A1ALOX15THRBCYP2C9CYP2C19 | |
| SCHEMBL11148538 | 0.92 | MME (0.58) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL10985113 | 0.90 | CTSL (0.51) | ALDH1A1ALOX15CTSLCTSBCTSS | |
| SCHEMBL8761906 | 0.88 | CTSL (0.52) | CTSLCTSBCTSSCTSKTRPM8 | |
| SCHEMBL9440145 | 0.88 | ALDH1A1 (0.59) | ALDH1A1ALOX15THRBCYP2C9CYP2C19 | |
| SCHEMBL9416814 | 0.88 | ALDH1A1 (0.62) | ALDH1A1ALOX15THRBCYP2C9CYP2C19 | |
| SCHEMBL11146459 | 0.87 | MME (0.61) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL10986547 | 0.87 | MME (0.52) | CTSLCTSBCTSSCTSKCAPN1 | |
| SCHEMBL8761927 | 0.86 | ECE1 (0.55) | CTSLCTSBCTSSCTSKCAPN1 | |
| SCHEMBL7757920 | 0.86 | MME (0.59) | CTSLCTSSCAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1985000809-A1 | THE SYNTHESIS OF CYCLOPROPANE AMINO ACIDS AND PEPTIDES | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 1985-02-28 | — | — | WO | disclosed |
| US-4119493-A | IN PRESENCE OF METALLOPROTEINASE ENZYME | (ZAIDANHOJIN) SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1978-10-10 | — | — | US | disclosed |
| US-4116768-A | AMIDATION, METALLOPROTEINASE ENZYME | (ZAIDANHOJIN) SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1978-09-26 | — | — | US | disclosed |
| US-3984417-A | Method of producing active amino acid esters | AJINOMOTO CO., INC. (JA) | 1976-10-05 | — | — | US | disclosed |
| US-3933783-A | Formation of peptide bonds in the presence of isonitriles | AJINOMOTO CO., INC. (JA) | 1976-01-20 | — | — | US | disclosed |