Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 4/20 | 0.61 |
| ▸ | ECE1 | P42892 | 3/20 | 0.61 |
| ▸ | ACE | P12821 | 3/20 | 0.56 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.53 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.53 |
| ▸ | TACR1 | P25103 | 2/20 | 0.52 |
| ▸ | CTSL | P07711 | 2/20 | 0.52 |
| ▸ | CTSB | P07858 | 2/20 | 0.52 |
| ▸ | CTSS | P25774 | 2/20 | 0.52 |
| ▸ | CTSK | P43235 | 2/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | CASP7 | P55210 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11148538 | 0.95 | MME (0.58) | MMEECE1ITGB3ITGA2BTACR1 | |
| SCHEMBL11211146 | 0.92 | TSHR (0.57) | MMEECE1ACETACR1CTSL | |
| SCHEMBL28252140 | 0.89 | ECE1 (0.64) | MMEECE1ACECTSLCTSB | |
| SCHEMBL8612642 | 0.89 | ECE1 (0.64) | MMEECE1ACECTSLCTSB | |
| SCHEMBL10986547 | 0.88 | MME (0.52) | MMEECE1TACR1CTSLCTSB | |
| SCHEMBL6271137 | 0.88 | CASP3 (0.64) | MMEECE1ACECTSLCTSB | |
| SCHEMBL10934632 | 0.87 | ALDH1A1 (0.57) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL8761906 | 0.87 | CTSL (0.52) | MMEECE1TACR1CTSLCTSB | |
| SCHEMBL10727026 | 0.87 | MME (0.67) | MMEECE1ITGB3ITGA2BTACR1 | |
| SCHEMBL20678118 | 0.87 | MME (0.67) | MMEECE1ITGB3ITGA2BTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4394308-A | Method of producing α-L-aspartyl-L-phenylalanine methylesters | CHIMICASA GMBH (CH) | 1983-07-19 | — | — | US | disclosed |
| US-4333872-A | Method of producing α-L-aspartyl-L-phenylalanine methylester | CHIMICASA GMBH (CH) | 1982-06-08 | — | — | US | disclosed |