Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CASP2 | P42575 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10936393 | 0.79 | NPC1 (0.58) | SMN1; SMN2NPC1RAB9ALMNAHPGD | |
| SCHEMBL10933809 | 0.78 | MAPT (0.50) | SMN1; SMN2NPC1RAB9ALMNAMAPT | |
| SCHEMBL10988958 | 0.76 | LMNA (0.54) | SMN1; SMN2NPC1RAB9ALMNAMAPT | |
| SCHEMBL10936135 | 0.73 | RAB9A (0.50) | SMN1; SMN2NPC1RAB9ACASP2MAPT | |
| SCHEMBL10933165 | 0.71 | ALDH1A1 (0.69) | LMNAHPGDHSD17B10MAPTKMT2A | |
| SCHEMBL10939456 | 0.70 | GAA (0.63) | NPC1RAB9ALMNAHPGDTSHR | |
| SCHEMBL11269297 | 0.70 | SMN1; SMN2 (0.47) | SMN1; SMN2NPC1RAB9ALMNAHPGD | |
| SCHEMBL10939352 | 0.70 | MAPT (0.45) | SMN1; SMN2NPC1RAB9ALMNAHPGD | |
| SCHEMBL10596956 | 0.69 | MEN1 (0.59) | SMN1; SMN2NPC1RAB9AMAPTKMT2A | |
| SCHEMBL10599620 | 0.68 | DYRK1A (0.51) | SMN1; SMN2NPC1RAB9AMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0051560-B1 | MONOAZOPIGMENTS CONTAINING HETEROCYCLIC NUCLEI, THEIR PREPARATION AND USE | CIBA-GEIGY AG (CH) | 1985-01-16 | — | — | EP | disclosed |
| US-4400319-A | Monoazo pigments containing heterocycles, and high-molecular organic materials dyed therewith | CIBA-GEIGY CORPORATION (US) | 1983-08-23 | — | — | US | disclosed |
| EP-0051560-A1 | Monoazopigments containing heterocyclic nuclei, their preparation and use | CIBA-GEIGY AG (CH) | 1982-05-12 | — | — | EP | disclosed |