Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | HTT | P42858 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | ACP1 | P24666 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10598617 | 0.84 | MEN1 (0.54) | RAB9ASMN1; SMN2NPC1MEN1KMT2A | |
| SCHEMBL10936271 | 0.84 | RAB9A (0.50) | RAB9ASMN1; SMN2NPC1MEN1KMT2A | |
| SCHEMBL3933070 | 0.79 | DYRK1A (0.72) | RAB9ASMN1; SMN2NPC1MEN1KMT2A | |
| SCHEMBL10872042 | 0.79 | NPC1 (0.53) | RAB9ASMN1; SMN2NPC1MEN1KMT2A | |
| SCHEMBL10933165 | 0.79 | ALDH1A1 (0.69) | MEN1KMT2AMAPK1ALDH1A1HTT | |
| SCHEMBL10936135 | 0.75 | RAB9A (0.50) | RAB9ASMN1; SMN2NPC1MAPK1ALDH1A1 | |
| SCHEMBL10935986 | 0.73 | DYRK1A (0.74) | RAB9ASMN1; SMN2NPC1MEN1KMT2A | |
| SCHEMBL10936133 | 0.73 | DYRK1A (0.74) | RAB9ASMN1; SMN2NPC1MEN1KMT2A | |
| SCHEMBL2753573 | 0.73 | POLB (0.60) | SMN1; SMN2MEN1KMT2AALDH1A1HTT | |
| SCHEMBL11848824 | 0.73 | NPC1 (0.44) | RAB9ASMN1; SMN2NPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0051560-B1 | MONOAZOPIGMENTS CONTAINING HETEROCYCLIC NUCLEI, THEIR PREPARATION AND USE | CIBA-GEIGY AG (CH) | 1985-01-16 | — | — | EP | disclosed |
| US-4400319-A | Monoazo pigments containing heterocycles, and high-molecular organic materials dyed therewith | CIBA-GEIGY CORPORATION (US) | 1983-08-23 | — | — | US | disclosed |
| EP-0051560-A1 | Monoazopigments containing heterocyclic nuclei, their preparation and use | CIBA-GEIGY AG (CH) | 1982-05-12 | — | — | EP | disclosed |