Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 2/20 | 0.54 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.54 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.54 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.54 |
| ▸ | CES2 | O00748 | 6/20 | 0.54 |
| ▸ | CES1 | P23141 | 5/20 | 0.54 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.53 |
| ▸ | CDC25B | P30305 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | FABP4 | P15090 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1920750 | 0.82 | CXCR2 (0.59) | CXCR2CDC25BNPC1RAB9AMEN1 | |
| SCHEMBL11498271 | 0.82 | AKR1C3 (0.53) | MAPK13MAPK12MAPK11MAPK14CXCR2 | |
| SCHEMBL11000813 | 0.81 | CXCR2 (0.63) | MAPK13MAPK12MAPK11MAPK14CXCR2 | |
| SCHEMBL1008928 | 0.80 | CXCR2 (0.68) | CXCR2CDC25BNPC1RAB9AMEN1 | |
| SCHEMBL29720861 | 0.80 | CXCR2 (0.68) | CXCR2CDC25BNPC1RAB9AMEN1 | |
| SCHEMBL1905196 | 0.79 | LIG1 (0.61) | MAPK13MAPK12MAPK11MAPK14CXCR2 | |
| SCHEMBL27435565 | 0.78 | CXCR2 (0.66) | CXCR2CDC25BMEN1TP53KMT2A | |
| SCHEMBL10741108 | 0.77 | CXCR2 (0.63) | CXCR2CDC25BMEN1TP53KMT2A | |
| SCHEMBL6760764 | 0.77 | MAPT (0.55) | CXCR2NPC1RAB9AMEN1TP53 | |
| SCHEMBL1921886 | 0.77 | CXCR2 (0.53) | CXCR2NPC1RAB9AMEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4529687-A | Low silver containing photographic material; developer is a nitrogen containing heterocyclic material | FUJI PHOTO FILM CO., LTD. (JP) | 1985-07-16 | — | — | US | disclosed |