Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.39 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14443234 | 0.82 | CA1 (0.51) | ALDH1A1LMNACA2CA1HPGD | |
| SCHEMBL1020457 | 0.82 | CA2 (0.55) | ALDH1A1TAS2R14CA2CA1RAB9A | |
| SCHEMBL16473924 | 0.80 | KDM4E (0.46) | ALDH1A1TAS2R14CA2CA1HPGD | |
| SCHEMBL2027640 | 0.80 | CA2 (0.59) | ALDH1A1POLBCA2CA1KMT2A | |
| SCHEMBL10060475 | 0.80 | ALDH1A1 (0.40) | ALDH1A1POLBCA2CA1MAPT | |
| SCHEMBL16225258 | 0.77 | SMN1; SMN2 (0.47) | ALDH1A1HTTLMNATAS2R14CA2 | |
| SCHEMBL10933934 | 0.77 | ALDH1A1 (0.48) | ALDH1A1TAS2R14HPGD | |
| SCHEMBL599583 | 0.77 | ENPP2 (0.54) | — | |
| SCHEMBL724893 | 0.76 | ALDH1A1 (0.50) | ALDH1A1POLBLMNAHPGDKMT2A | |
| SCHEMBL14464916 | 0.76 | ALDH1A1 (0.38) | ALDH1A1TAS2R14CA2CA1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0041711-B1 | 6-CHLORO- OR 6-BROMO-1,2-DIHYDRO-3H-PYRROLO(1,2-A)-PYRROLE-1-CARBOXYLIC ACIDS AND DERIVATIVES THEREOF, PROCESS FOR THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SYNTEX (U.S.A.) INC. (US) | 1985-04-17 | — | — | EP | disclosed |
| US-4344943-A | ANALGESICS, ANTIINFLAMMATORY AGENTS | SYNTEX (U.S.A.) INC. (US) | 1982-08-17 | — | — | US | disclosed |
| EP-0041711-A1 | 6-Chloro- or 6-bromo-1,2-dihydro-3H-pyrrolo(1,2-a)-pyrrole-1-carboxylic acids and derivatives thereof, process for their production and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1981-12-16 | — | — | EP | disclosed |