Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.54 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.50 |
| ▸ | GSR | P00390 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.49 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.47 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17981319 | 0.94 | PTGS2 (0.54) | ENPP2AKR1C3GSRMAOBPTGS2 | |
| SCHEMBL724893 | 0.81 | ALDH1A1 (0.50) | — | |
| SCHEMBL4321082 | 0.81 | ENPP2 (0.58) | ENPP2AKR1C3GSRPTGS2 | |
| SCHEMBL28079560 | 0.79 | ENPP2 (0.47) | ENPP2AKR1C3GSRMAOBPTGS2 | |
| SCHEMBL35155 | 0.79 | ALDH1A1 (0.48) | MAOB | |
| SCHEMBL28229 | 0.79 | PTGS2 (0.57) | ENPP2AKR1C3GSRPTGS2 | |
| SCHEMBL8747696 | 0.79 | LMNA (0.52) | — | |
| SCHEMBL34837 | 0.79 | CA2 (0.61) | ENPP2AKR1C3GSRPTGS2 | |
| SCHEMBL10451127 | 0.78 | PSIP1 (0.50) | — | |
| SCHEMBL9659082 | 0.77 | LMNA (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 229 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1506355-A | Diphenyl benzimidazole compound containing sulfonyl group and its prepn process, medicinal composition and use | 中国医学科学院药物研究所 | 2004-06-23 | — | — | CN | claimed |
| CN-122010767-A | Haloalkyl bisamide compound and application thereof | 山东熙霖生物科技有限公司 | 2026-05-12 | — | — | CN | disclosed |
| US-20250145598-A1 | ACID CERAMIDASE INHIBITORS AND USES THEREOF | UNIV CALIFORNIA (US) | 2025-05-08 | — | — | US | disclosed |
| CN-115626894-B | Lappaconitine derivative with analgesic activity, and preparation method and application thereof | 西南交通大学 | 2025-04-18 | — | — | CN | disclosed |
| CN-119409623-A | Ketoxime ester photoinitiator and application thereof, and photosensitive composition | 武汉尚赛光电科技有限公司 | 2025-02-11 | — | — | CN | disclosed |
| CN-111936471-B | Non-fused thiophene derivatives and uses thereof | 埃尼奥制药公司 | 2024-10-29 | — | — | CN | disclosed |
| US-20240342185-A1 | SMALL MOLECULES INHIBITORS OF CYCLIC GMP-AMP SYNTHASE (cGAS) | SHANGPHARMA INNOVATION INC. | 2024-10-17 | — | — | US | disclosed |
| EP-4387617-A1 | ACID CERAMIDASE INHIBITORS AND USES THEREOF | The Regents of the University of California (US) | 2024-06-26 | — | — | EP | disclosed |
| CN-112708644-B | Preparation method of florfenicol intermediate | 弈柯莱生物科技(集团)股份有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-118026883-A | Amide compound and preparation method and application thereof | 南通泰禾化工股份有限公司 | 2024-05-14 | — | — | CN | disclosed |
| WO-1995017485-A1 | FUEL COMPOSITIONS CONTAINING POLYALKYL AND POLY(OXYALKYLENE) AROMATIC ESTERS | CHEVRON CHEMICAL COMPANY (US) | 1995-06-29 | — | — | WO | disclosed |
| EP-0596326-A1 | Arylidene-1-azacycloalkanes and arylalkyl-1-azacycloalkanes, their salts, medicaments containing the same, use thereof and precesses for their production | Dr. Karl Thomae GmbH (DE) | 1994-05-11 | — | — | EP | disclosed |
| US-4609610-A | BY BETA-ELIMINATION | EASTMAN KODAK COMPANY (US) | 1986-09-02 | — | — | US | disclosed |
| US-4425282-A | Preparation of 3-(arylvinyl)-2,2-dimethyl-cyclopropane-1-carboxylic acid esters and new intermediate therefor | BAYER AKTIENGESELLSCHAFT (DE) | 1984-01-10 | — | — | US | disclosed |
| EP-0018533-B1 | SUBSTITUTED PENTANE (OR PENTENE) CARBOXYLIC ACIDS AND THEIR DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE FOR THE PREPARATION OF 3-(ARYLVINYL)-2,2-DIMETHYL-CYCLOPROPANE-1-CARBOXYLATES | BAYER AG (DE) | 1983-01-26 | — | — | EP | disclosed |
| US-4329456-A | ACYLATION WITHOUT INTERMEDIATE ISOLATION | CIBA-GEIGY AG (CH) | 1982-05-11 | — | — | US | disclosed |
| US-4269848-A | ANTIINFLAMMATORY AGENTS; ANALGESICS; ANTIPYRETICS | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1981-05-26 | — | — | US | disclosed |
| EP-0018533-A1 | Substituted pentane (or pentene) carboxylic acids and their derivatives, process for their preparation and their use for the preparation of 3-(arylvinyl)-2,2-dimethyl-cyclopropane-1-carboxylates | BAYER AG (DE) | 1980-11-12 | — | — | EP | disclosed |
| US-4224341-A | ANTIINFLAMMATORY AGENTS, ANALGESICS AND ANTIPYRETICS | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1980-09-23 | — | — | US | disclosed |
| US-4057642-A | ANTIINFLAMMATORY, RHEUMATOID ARTHRITIS | MERCK & CO., INC. (US) | 1977-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250145598-A1 | ACID CERAMIDASE INHIBITORS AND USES THEREOF | ASAH2, ASAH1, ACER2 | ENPP2 18/4885AKR1C3 1418/4885GSR 3736/4885 |
| US-20240342185-A1 | SMALL MOLECULES INHIBITORS OF CYCLIC GMP-AMP SYNTHASE (cGAS) | CGAS, GMPS, PRKG1 | ENPP2 454/4885AKR1C3 2584/4885GSR 539/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.