Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 7/20 | 0.62 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.62 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.62 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.61 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11226933 | 0.84 | ADRB2 (0.66) | ADRB3ADRB2ADRB1PTGS1SLC6A2 | |
| SCHEMBL11718737 | 0.82 | ADRB2 (0.43) | ADRB3ADRB2ADRB1 | |
| SCHEMBL11718729 | 0.82 | ADRB2 (0.43) | ADRB3ADRB2ADRB1 | |
| SCHEMBL11284468 | 0.81 | PTGS1 (0.79) | ADRB3ADRB2ADRB1PTGS1SLC6A2 | |
| SCHEMBL6321893 | 0.77 | ADRB2 (0.65) | ADRB3ADRB2ADRB1 | |
| SCHEMBL6321887 | 0.77 | ADRB2 (0.65) | ADRB3ADRB2ADRB1 | |
| Prenalterol SCHEMBL249753 | 0.77 | PTGS1 (1.00) | ADRB3ADRB2ADRB1PTGS1SLC6A2 | |
| Prenalterol SCHEMBL10788435 | 0.77 | PTGS1 (1.00) | ADRB3ADRB2ADRB1PTGS1SLC6A2 | |
| Prenalterol SCHEMBL10816429 | 0.77 | PTGS1 (1.00) | ADRB3ADRB2ADRB1PTGS1SLC6A2 | |
| SCHEMBL11066158 | 0.77 | ADRB3 (0.58) | ADRB3ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336267-A | Heart active compounds and methods of use | AKTIEBOLAGET HASSLE (SE) | 1982-06-22 | — | — | US | claimed |
| EP-0041492-B1 | NEW SUBSTITUTED 3-PHENOXY-1-ALKOXYCARBONYL-ALKYLAMINO-PROPANOL-2-S HAVING BETA RECEPTOR BLOCKING PROPERTIES | Aktiebolaget Hässle (SE) | 1985-03-20 | — | — | EP | disclosed |
| US-4336267-A | Heart active compounds and methods of use | AKTIEBOLAGET HASSLE (SE) | 1982-06-22 | — | — | US | disclosed |
| US-4244969-A | (P-HYDROXYPHENOXY)PROPANOLAMINE DERIVATIVES USEFUL AS B-RECEPTOR STIMULANTS | AKTIEBOLAGET HASSLE (SE) | 1981-01-13 | — | — | US | disclosed |